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[丹参酮II(A)心血管效应的研究进展]

[Advances in cardiovascular effects of tanshinone II(A)].

作者信息

Chen Fen-yan, Guo Ren, Zhang Bi-kui

出版信息

Zhongguo Zhong Yao Za Zhi. 2015 May;40(9):1649-53.

Abstract

Cardiovascular diseases, like coronary heart disease and myocardial infarction, are the most common cause of death worldwide. Chinese medicines have demonstrated rich cardioprotective activities for clinical applications. Salvia miltiorrhiza, a very important component of traditional Chinese medicine, can promote blood circulation and relieve blood stasis. Salvia miltiorrhiza is widely used in treatment of cardiovascular and cerebrovascular disease such as coronary heart disease and cerebral infarction ( CI). Tanshinone II(A), the major lipophilic components extracted from the root of S. miltiorrhiza, possesses anti-atherosclerosis, anti-cardiac hypertrophy, anti-oxidant, anti-arrhythmia and so on. This paper discusses current research status of tanshinone II(A) in cardioprotective effects.

摘要

心血管疾病,如冠心病和心肌梗死,是全球最常见的死亡原因。中药已显示出丰富的心脏保护活性,可用于临床应用。丹参是传统中药的重要组成部分,具有活血化瘀的作用。丹参广泛应用于治疗心血管和脑血管疾病,如冠心病和脑梗死(CI)。丹参酮II(A)是从丹参根中提取的主要亲脂性成分,具有抗动脉粥样硬化、抗心肌肥厚、抗氧化、抗心律失常等作用。本文探讨了丹参酮II(A)在心脏保护作用方面的研究现状。

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