Jain Keerti, Mehra Neelesh Kumar, Jain Narendra K
Pharmaceutical Nanotechnoloagy Research Laboratory, ISF College of Pharmacy, Moga (Punjab) 142001, India.
Curr Pharm Des. 2015;21(29):4252-61. doi: 10.2174/1381612821666150901103208.
Nanotoxicology deals with the new perception regarding nanotechnology i.e. risk and hazards associated with nanoscale materials. Although, nanotechnology is playing significant role in modern advancements from cell phones to medicines, yet it is necessary to consider their negative part as well that could be dangerous if not given proper attention. It is not certain that nanotechnology will essentially exert toxic effects since at present only few reports are available on their toxic effects and most of them are controversial. In this review we have summarized the advances in nanotechnology, their applications and, most importantly their safety issues that are often overlooked. However combined efforts are advocated to develop promising regulatory and ethical guidelines to control production, use and disposal of nanomaterials that will be safe to human health, environment and other living organisms.
纳米毒理学涉及对纳米技术的新认识，即与纳米级材料相关的风险和危害。尽管纳米技术在从手机到药物的现代进步中发挥着重要作用，但也有必要考虑其负面因素，如果不给予适当关注，这些因素可能会很危险。目前尚不确定纳米技术是否会产生毒性作用，因为目前关于其毒性作用的报道很少，而且大多数报道都存在争议。在这篇综述中，我们总结了纳米技术的进展、其应用，以及最重要的是那些经常被忽视的安全问题。然而，提倡各方共同努力，制定有前景的监管和道德准则，以控制纳米材料的生产、使用和处置，使其对人类健康、环境和其他生物安全无害。
