Gellerfors Mikael, Linde Joacim, Gryth Dan
1Karolinska Institutet/Södersjukhuset,Department of Clinical Science and Education,Section of Anesthesiology and Intensive Care,Stockholm,Sweden.
2SAE Medevac Helicopter,Armed Forces Centre for Defense Medicine (FörmedC),Gothenburg,Sweden.
Prehosp Disaster Med. 2015 Oct;30(5):509-11. doi: 10.1017/S1049023X15005014. Epub 2015 Sep 1.
Massive hemorrhage with coagulopathy is one of the leading causes of preventable death in the battlefield. The development of freeze-dried plasma (FDP) allows for early treatment with coagulation-optimizing resuscitation fluid in the prehospital setting. This report describes the first prehospital use of FDP in a patient with carotid artery injury due to a high-velocity gunshot wound (HVGSW) to the neck. It also describes in-flight constitution and administration of FDP in a Medevac Helicopter. Early administration of FDP may contribute to hemodynamic stabilization and reduction in trauma-induced coagulopathy and acidosis. However, large-scale studies are needed to define the prehospital use of FDP and other blood products.
大出血合并凝血功能障碍是战场上可预防死亡的主要原因之一。冻干血浆（FDP）的研制使得在院前环境中能够使用优化凝血的复苏液进行早期治疗。本报告描述了FDP首次在一名因颈部高速枪伤（HVGSW）导致颈动脉损伤的患者的院前使用情况。还描述了在医疗后送直升机上FDP的飞行中配制和给药情况。早期给予FDP可能有助于血流动力学稳定，并减少创伤性凝血功能障碍和酸中毒。然而，需要大规模研究来确定FDP和其他血液制品在院前的使用情况。
