肺癌患者综合护理对生活质量影响的荟萃分析。

A meta-analysis of comprehensive care on quality of life in patients with lung cancer.

作者信息

Wang Xiang, Cao Haili

机构信息

Department of Emergency, Huaihe Hospital of Henan University, Henan, Kaifeng 475000, China.

出版信息

J Cancer Res Ther. 2015 Aug;11 Suppl 1:C112-4. doi: 10.4103/0973-1482.163860.

DOI:10.4103/0973-1482.163860

PMID:26323907

Abstract

OBJECTIVE

The aim of this meta-analysis was to evaluate the efficacy of comprehensive care on quality of life in patients with lung cancer.

METHODS

The clinical studies about comprehensive care on quality of life in patients with lung cancer were searched in the Medline, PubMed, EMBASE, CNKI, and WANFANG databases. The score of society function, emotional function, somatic function, cognitive function was collected in each of the included studies. And the data were pooled by Stata version 11.0 software.

RESULT

Finally, three clinical studies including 536 cases were included in this meta-analysis. Significant statistical heterogeneity was existed in the three papers (P < 0.05). The data were pooled by random effect model. The combined results showed that the quality of life for lung cancer patients can be significantly improved in the aspects of society function (standardized mean difference [SMD] =0.41, 95% confidence interval [CI]: 0.10-0.71), emotional function (SMD = 0.45, 0.12-0.78), somatic function (SMD = 0.98, 95% CI: 0.51-1.44), and cognitive function (SMD = 0.64, 95% CI: 0.44-0.83).

CONCLUSION

Quality of life for lung cancer patients can be significantly improved through comprehensive care.

摘要

目的

本荟萃分析旨在评估综合护理对肺癌患者生活质量的疗效。

方法

在Medline、PubMed、EMBASE、中国知网和万方数据库中检索关于肺癌患者综合护理对生活质量影响的临床研究。收集纳入研究中每项的社会功能、情感功能、躯体功能、认知功能评分。并采用Stata 11.0软件对数据进行汇总。

结果

最终，本荟萃分析纳入3项临床研究，共536例患者。这3篇论文存在显著的统计学异质性（P<0.05）。采用随机效应模型对数据进行汇总。合并结果显示，肺癌患者的生活质量在社会功能（标准化均数差[SMD]=0.41，95%置信区间[CI]：0.10-0.71）、情感功能（SMD=0.45，0.12-0.78）、躯体功能（SMD=0.98，95%CI：0.51-1.44）和认知功能（SMD=0.64，95%CI：0.44-0.83）方面均可得到显著改善。