Rutkowska Anna, Rutkowski Sebastian, Wrzeciono Adam, Czech Oliver, Szczegielniak Jan, Jastrzębski Dariusz
Faculty of Physical Education and Physiotherapy, Opole University of Technology, 45-758 Opole, Poland.
Descartes' Error Student Research Association, Faculty of Physical Education and Physiotherapy, Opole University of Technology, 45-758 Opole, Poland.
J Clin Med. 2021 Apr 18;10(8):1761. doi: 10.3390/jcm10081761.
The aim of this study was to assess the impact of exercise training on the quality of life (QoL) of patients diagnosed with stage IIIB and stage IV non-small cell lung cancer (NSCLC) compared to a passive control group (CG). The exercise-trained group (ETG) consisted of 18 patients, and the CG consisted of 8 patients. The training program in the ETG consisted of two 2-week running cycles interspersed with consecutive rounds of chemotherapy with cytostatic drugs. A comparison of the changes in the Short Form (36) Health Survey (SF-36), St. George's Respiratory Questionnaire (SGRQ), and the Functional Assessment of Cancer Therapy-Lung (FACT-L) was the primary outcome. Analysis of the results of the SGRQ and the SF-36 questionnaire did not reveal any statistically significant differences in the assessment of QoL between the examined groups. The analysis of FACT-L questionnaires showed statistically significant changes, indicating deterioration of QoL in domains describing physical well-being in the CG. Therefore, the analysis of the results of the QoL assessment did not show any significant improvements in the group of patients undergoing comprehensive exercise training, although deterioration of QoL was noted in the CG.
本研究的目的是评估运动训练对诊断为IIIB期和IV期非小细胞肺癌（NSCLC）患者生活质量（QoL）的影响，并与被动对照组（CG）进行比较。运动训练组（ETG）由18名患者组成，CG组由8名患者组成。ETG的训练计划包括两个为期2周的跑步周期，期间穿插连续几轮使用细胞毒性药物的化疗。比较简短健康调查（SF-36）、圣乔治呼吸问卷（SGRQ）和癌症治疗功能评估-肺癌（FACT-L）的变化是主要结果。对SGRQ和SF-36问卷结果的分析未发现所检查组之间在生活质量评估方面有任何统计学上的显著差异。对FACT-L问卷的分析显示有统计学上的显著变化，表明CG组中描述身体健康的领域的生活质量有所恶化。因此，生活质量评估结果的分析并未显示接受综合运动训练的患者组有任何显著改善，尽管CG组中生活质量出现了恶化。
