Zhang Hui, Meng Xianglin
Department of General Surgery, The First Affiliated Hospital of Anhui Medical University, Anhui 230032, China.
J Cancer Res Ther. 2015 Aug;11 Suppl 1:C122-4. doi: 10.4103/0973-1482.163867.
The purpose of this study was to evaluate the postoperative complications for patients with adenocarcinoma of esophagogastric junction.
Two hundred and eighty subjects with adenocarcinoma of esophagogastric junction who received operation were retrospectively analyzed from June 2006 to December 2010 in the Department of Oncology of First Affiliated Hospital of Bengbu Medical College, Bengbu, China. The postoperative complication such as ventricular premature beat, atrial fibrillation, supraventricular tachycardia, heart failure, pulmonary infection, pulmonary atelectasis, respiratory failure, bronchospasm, anastomotic leakage, gastroplegia, pleural infection, and cerebral accident were reviewed and recorded by to doctors. Moreover, the correlation between clinical characteristics and postoperative complication was analyzed by statistical methods.
A total of 70 complications were found for the included 280 cases of adenocarcinoma of esophagogastric junction with general incidence of 25%. For the relationship between clinical characteristics and postoperative complication analysis, no significant association of gender, age, operation time, operative approach, tumor differentiation, and clinical states was found with the postoperative complications (P > 0.05); but the complication rate in patients with basic disease of heart and lung was significant than the patients without this kind of disease (P < 0.05).
The positive operative complications for patients with adenocarcinoma of esophagogastric junction were relative high. Moreover, basic heart and lung diseases can increase the risk of developing positive operative complications.
本研究旨在评估食管胃交界腺癌患者的术后并发症。
回顾性分析2006年6月至2010年12月在中国蚌埠医学院第一附属医院肿瘤科接受手术的280例食管胃交界腺癌患者。医生对术后并发症如室性早搏、心房颤动、室上性心动过速、心力衰竭、肺部感染、肺不张、呼吸衰竭、支气管痉挛、吻合口漏、胃瘫、胸膜感染和脑卒中等进行了检查和记录。此外,采用统计学方法分析临床特征与术后并发症之间的相关性。
纳入的280例食管胃交界腺癌患者共发现70例并发症,总发生率为25%。对于临床特征与术后并发症关系的分析,未发现性别、年龄、手术时间、手术方式、肿瘤分化程度和临床状态与术后并发症有显著相关性(P>0.05);但有心肺基础疾病患者的并发症发生率显著高于无此类疾病的患者(P<0.05)。
食管胃交界腺癌患者的手术相关并发症发生率相对较高。此外,心肺基础疾病会增加手术相关并发症发生的风险。