Deshmukh B D, Suryawanshi S A
Indian J Exp Biol. 1989 Sep;27(9):780-4.
Effects of single, whole-body 60Co-gamma irradiation in different doses (250 rad to 15 k rad) on histology of thyroid, adrenal and pancreatic islets of the rain quail were studied. A low dose of 250 rad failed to evoke any change in histology of the glands studied. Doses of 500 rad and 1 k rad resulted in hypoactivity of thyroid but could not affect adrenal and pancreatic islets. Exposure to 1.5 k rad and higher doses caused hyperplasia and hypertrophy of thyroid and hypertrophy of adrenal gland. Thyroid was injured by heavy irradiation. Doses up to 3 k rad did not bring about any change in islet cells, however, higher doses resulted in degenerative changes in islet cells. alpha-islets were affected by 7 and 15 k rad but necrotic changes in beta-islets were observed only after exposure to 15 k rad. The results indicate that thyroid is the most sensitive and pancreatic islet, highly resistant to gamma radiation.
研究了不同剂量（250拉德至15千拉德）的单次全身60钴-γ辐射对雨鹌鹑甲状腺、肾上腺和胰岛组织学的影响。低剂量250拉德未能引起所研究腺体组织学的任何变化。500拉德和1千拉德的剂量导致甲状腺功能减退，但不影响肾上腺和胰岛。暴露于1.5千拉德及更高剂量会导致甲状腺增生和肥大以及肾上腺肥大。重度辐射会损伤甲状腺。3千拉德以下的剂量不会引起胰岛细胞的任何变化，然而，更高剂量会导致胰岛细胞发生退行性变化。α-胰岛受到7千拉德和15千拉德的影响，但仅在暴露于15千拉德后才观察到β-胰岛的坏死变化。结果表明，甲状腺对γ辐射最敏感，而胰岛对γ辐射具有高度抗性。
