Vrancx S, Van de Sande J, Vanclooster P, de Gheldere C, Van de Velde A
Department of General Surgery, H.-Hartziekenhuis Lier, Belgium.
Acta Chir Belg. 2015 Jul-Aug;115(4):306-9. doi: 10.1080/00015458.2015.11681117.
Burkitt lymphoma belongs to the B cell non-Hodgkin tumors and is known as the fastest growing human tumor. It is mostly seen in children and young adults. Typically for this type of lymphoma is the chromosomal translocation that leads to a deregulated expression of the c-myc oncogene. Our case report describes a 17 year old patient who presents with atypical right lower quadrant pain. He underwent an explorative laparoscopy and a Burkitt lymphoma was discovered. Subsequently several imaging studies were performed to stage the disease. Intensive systemic chemotherapy is the choice of treatment. Surgery can have a role in early stages and acute complications of the tumor but frequently the role of surgery is restricted to histological biopsy.
伯基特淋巴瘤属于B细胞非霍奇金肿瘤，是已知生长速度最快的人类肿瘤。多见于儿童和青年。这种类型淋巴瘤的典型特征是染色体易位，导致c-myc原癌基因表达失调。我们的病例报告描述了一名17岁患者，他表现为非典型性右下腹疼痛。他接受了 exploratory laparoscopy（此处原文有误，推测为exploratory laparotomy，即剖腹探查术），并发现了伯基特淋巴瘤。随后进行了几项影像学检查以对疾病进行分期。强化全身化疗是治疗的选择。手术在肿瘤的早期阶段和急性并发症中可能起作用，但手术的作用通常仅限于组织学活检。
