全身FDG PET成像中腮腺局灶性FDG摄取的病理结果预测因素。
Predictors of pathologic outcome of focal FDG uptake in the parotid gland identified on whole-body FDG PET imaging.
作者信息
Mabray Marc C, Behr Spencer C, Naeger David M, Flavell Robert R, Glastonbury Christine M
机构信息
Department of Radiology and Biomedical Imaging, University of California, San Francisco, 505 Parnassus Ave, San Francisco CA 94143.
Department of Radiology and Biomedical Imaging, University of California, San Francisco, 505 Parnassus Ave, San Francisco CA 94143.
出版信息
Clin Imaging. 2015 Nov-Dec;39(6):1073-9. doi: 10.1016/j.clinimag.2015.07.005. Epub 2015 Jul 16.
Abstract
PURPOSE
The purpose was to test whether patient's primary malignancy type and presence of F-18-fluorodeoxyglucose (FDG)-avid cervical lymph node(s) are predictors of pathologic outcome of incidental focal FDG-avid parotid lesions.
BASIC PROCEDURES
A retrospective cohort study of pathologically proven incidental cases was performed.
MAIN FINDINGS
Focal parotid FDG uptake in the setting of head and neck cancer/melanoma [odds ratio (OR)=24.6, P<.01], lymphoma (OR=7.2, P=.02), or FDG-avid cervical lymph node(s) (OR=3.6, P=.07) has a higher odds of representing metastases. No malignant primary parotid tumors were incidentally discovered.
PRINCIPAL CONCLUSIONS
In patients with head and neck cancer/melanoma, lymphoma, or FDG-avid cervical lymph node(s), there were higher odds that focal parotid FDG uptake was a metastasis.
摘要
目的
旨在测试患者的原发性恶性肿瘤类型以及F-18氟脱氧葡萄糖（FDG）摄取阳性的颈部淋巴结是否为偶然发现的局灶性FDG摄取阳性腮腺病变病理结果的预测因素。
基本程序
对经病理证实的偶然病例进行回顾性队列研究。
主要发现
在头颈部癌/黑色素瘤[比值比（OR）=24.6，P<0.01]、淋巴瘤（OR=7.2，P=0.02）或FDG摄取阳性的颈部淋巴结（OR=3.6，P=0.07）的情况下，腮腺局灶性FDG摄取更有可能代表转移瘤。未偶然发现原发性腮腺恶性肿瘤。
主要结论
在患有头颈部癌/黑色素瘤、淋巴瘤或FDG摄取阳性的颈部淋巴结的患者中，腮腺局灶性FDG摄取更有可能是转移瘤。
相似文献
1
Predictors of pathologic outcome of focal FDG uptake in the parotid gland identified on whole-body FDG PET imaging.全身FDG PET成像中腮腺局灶性FDG摄取的病理结果预测因素。
Clin Imaging. 2015 Nov-Dec;39(6):1073-9. doi: 10.1016/j.clinimag.2015.07.005. Epub 2015 Jul 16.
2
Incidental focal FDG uptake in the parotid glands on PET/CT in patients with head and neck malignancy.头颈部恶性肿瘤患者 PET/CT 检查中偶然发现的腮腺局灶性 FDG 摄取。
Eur Radiol. 2015 Jan;25(1):171-7. doi: 10.1007/s00330-014-3397-1. Epub 2014 Sep 3.
3
Clinical significance of parotid gland incidentalomas on (18)F-FDG PET/CT.腮腺偶发瘤在（18）F-FDG PET/CT上的临床意义
Clin Imaging. 2015 Jul-Aug;39(4):667-71. doi: 10.1016/j.clinimag.2015.03.011. Epub 2015 Apr 7.
4
Significance of incidental fluorodeoxyglucose uptake in the parotid glands and its impact on patient management.腮腺中偶然出现的氟脱氧葡萄糖摄取的意义及其对患者管理的影响。
Nucl Med Commun. 2008 Apr;29(4):367-73. doi: 10.1097/MNM.0b013e3282f8147a.
5
Efficacy of conventional whole-body ¹⁸F-FDG PET/CT in the incidental findings of parotid masses.常规全身¹⁸F-FDG PET/CT 在腮腺肿块偶然发现中的功效。
Ann Nucl Med. 2010 Oct;24(8):571-7. doi: 10.1007/s12149-010-0394-6. Epub 2010 Jul 17.
6
Incidental [18F]FDG-avid focuses in parotid glands on PET/CT.PET/CT上腮腺内偶然发现的[18F]FDG摄取灶。
Acta Otolaryngol. 2024 Feb;144(2):147-152. doi: 10.1080/00016489.2024.2328720. Epub 2024 Mar 26.
7
Focal fluorine-18 fluorodeoxyglucose-avid lesions without computed tomography correlate at whole-body positron emission tomography-computed tomography in oncology patients: how often are they malignant?在肿瘤患者的全身正电子发射断层扫描-计算机断层扫描中，氟-18氟脱氧葡萄糖摄取灶在计算机断层扫描上无对应表现：这些病灶为恶性的频率有多高？
Nucl Med Commun. 2011 Sep;32(9):802-7. doi: 10.1097/MNM.0b013e3283483e04.
8
Focal fluorine-18 fluorodeoxyglucose-avid parotid findings in patients with lung cancer: prevalence and characteristics.肺癌患者腮腺出现局灶性氟-18氟脱氧葡萄糖摄取：患病率及特征
Nucl Med Commun. 2016 Sep;37(9):969-74. doi: 10.1097/MNM.0000000000000543.
9
False-Positive [18F]fluorodeoxyglucose-avid lymph nodes on positron emission tomography-computed tomography after allogeneic but not autologous stem-cell transplantation in patients with lymphoma.淋巴瘤患者异基因而非自体干细胞移植后正电子发射断层扫描-计算机断层扫描上出现氟脱氧葡萄糖阳性的淋巴结假阳性。
J Clin Oncol. 2014 Jan 1;32(1):51-6. doi: 10.1200/JCO.2013.50.8044. Epub 2013 Nov 18.
10
Feasibility of a multimodal (18)F-FDG-directed lymph node surgical excisional biopsy approach for appropriate diagnostic tissue sampling in patients with suspected lymphoma.疑似淋巴瘤患者采用多模态 (18)F-FDG 引导的淋巴结手术切除活检方法进行适当诊断性组织取样的可行性。
BMC Cancer. 2015 May 8;15:378. doi: 10.1186/s12885-015-1381-z.
引用本文的文献
1
Incidentalomas in the head & neck.头颈部意外瘤。
Br J Radiol. 2023 Feb;96(1142):20220164. doi: 10.1259/bjr.20220164. Epub 2022 Nov 28.
2
Prevalence and Clinical Implications of Incidentally Detected Parotid Lesions as Blind Spot on Brain MRI: A Single-Center Experience.脑 MRI 检查中偶然发现的腮腺病变的流行情况及其临床意义：单中心经验。
Medicina (Kaunas). 2021 Aug 18;57(8):836. doi: 10.3390/medicina57080836.
3
Clinicopathological features of incidental parotid lesions.偶然发现的腮腺病变的临床病理特征。
Head Face Med. 2021 Mar 23;17(1):10. doi: 10.1186/s13005-021-00262-6.
4
Evidence-based management of incidental focal uptake of fluorodeoxyglucose on PET-CT.基于证据的正电子发射断层扫描-计算机断层扫描（PET-CT）上氟脱氧葡萄糖偶然局灶性摄取的管理
Br J Radiol. 2018 Apr;91(1084):20170774. doi: 10.1259/bjr.20170774. Epub 2018 Jan 31.
本文引用的文献
1
Prevalence and risk of malignancy of focal incidental uptake detected by fluorine-18-fluorodeoxyglucose positron emission tomography in the parotid gland: a meta-analysis.18F-氟脱氧葡萄糖正电子发射断层扫描检测腮腺局灶性偶然摄取的恶性肿瘤患病率及风险：一项荟萃分析
Eur Arch Otorhinolaryngol. 2015 Dec;272(12):3617-26. doi: 10.1007/s00405-014-3308-8. Epub 2014 Sep 28.
2
Incidental focal FDG uptake in the parotid glands on PET/CT in patients with head and neck malignancy.头颈部恶性肿瘤患者 PET/CT 检查中偶然发现的腮腺局灶性 FDG 摄取。
Eur Radiol. 2015 Jan;25(1):171-7. doi: 10.1007/s00330-014-3397-1. Epub 2014 Sep 3.
3
The value of preoperative 18F-FDG PET/CT for the assessing contralateral neck in head and neck cancer patients with unilateral node metastasis (N1-3).术前18F-FDG PET/CT对单侧淋巴结转移（N1-3）的头颈癌患者对侧颈部评估的价值
Clin Otolaryngol. 2014 Dec;39(6):338-44. doi: 10.1111/coa.12295.
4
Diagnostic Criteria on (18)F-FDG PET/CT for Differentiating Benign from Malignant Focal Hypermetabolic Lesions of Parotid Gland.(18)F-FDG PET/CT鉴别腮腺局灶性高代谢病变良恶性的诊断标准
Nucl Med Mol Imaging. 2012 Jun;46(2):95-101. doi: 10.1007/s13139-012-0135-y. Epub 2012 Apr 21.
5
Clinical significance of incidental findings on staging positron emission tomography for oesophagogastric malignancies.食管胃恶性肿瘤分期正电子发射断层扫描中偶然发现的临床意义。
Ann R Coll Surg Engl. 2014 Apr;96(3):207-10. doi: 10.1308/003588414X13814021678871.
6
The Proportion of Malignancy in Incidental Thyroid Lesions on 18-FDG PET Study: A Systematic Review and Meta-analysis.18氟脱氧葡萄糖正电子发射断层扫描研究中偶然发现的甲状腺病变的恶性比例：一项系统评价和荟萃分析。
Otolaryngol Head Neck Surg. 2014 Aug;151(2):190-200. doi: 10.1177/0194599814530861. Epub 2014 Apr 23.
7
Frequency and clinical implications of incidental new primary cancers detected on true whole-body 18F-FDG PET/CT studies.在真正的全身 18F-FDG PET/CT 检查中检测到的偶发性新发原发性癌症的频率及临床意义。
Nucl Med Commun. 2013 Apr;34(4):333-9. doi: 10.1097/MNM.0b013e32835f163f.
8
Parotid gland tumors: preliminary data for the value of FDG PET/CT diagnostic parameters.腮腺肿瘤：FDG PET/CT 诊断参数价值的初步数据。
AJR Am J Roentgenol. 2012 Feb;198(2):W185-90. doi: 10.2214/AJR.11.7172.
9
Clinical significance of incidental focal colorectal (18)F-fluorodeoxyglucose uptake: our experience and a review of the literature.偶然发现的局灶性结直肠（18）F-氟脱氧葡萄糖摄取的临床意义：我们的经验和文献复习。
Colorectal Dis. 2012 Feb;14(2):174-80. doi: 10.1111/j.1463-1318.2011.02588.x.
10
Incidental focal 18F-FDG uptake in the pituitary gland: clinical significance and differential diagnostic criteria.垂体偶然摄取 18F-FDG：临床意义和鉴别诊断标准。
J Nucl Med. 2011 Apr;52(4):547-50. doi: 10.2967/jnumed.110.083733. Epub 2011 Mar 18.
Zotero 插件