Kreiser Nicole L, White Susan W
Department of Psychology, Virginia Tech, 109 Williams Hall, Blacksburg, VA, 24061, USA.
Department of Neuropsychology, Kennedy Krieger Institute/Johns Hopkins School of Medicine, 1750 East Fairmount Ave, Baltimore, MD, 21231, USA.
J Autism Dev Disord. 2015 Dec;45(12):3932-8. doi: 10.1007/s10803-015-2580-9.
The higher prevalence of autism spectrum disorder (ASD) in males, relative to that seen in females, is a well-replicated phenomenon. A growing body of research has suggested that there may be gender differences in core ASD deficits and patterns of psychiatric comorbidity among adolescents and adults with ASD. The present study sought to determine if association between psychiatric diagnoses and ASD traits differed by gender in a young adult analogue sample. Participants (n = 84) were university students, scoring either above or below a pre-determined cut-off of ASD traits. Using a structured psychiatric screening interview, ASD traits were found to more strongly predict exceeding screening threshold for mood disorders in females than in males. Future directions and clinical implications are discussed.
与女性相比，男性自闭症谱系障碍（ASD）的患病率更高，这是一个得到充分验证的现象。越来越多的研究表明，患有ASD的青少年和成年人在ASD核心缺陷及精神共病模式方面可能存在性别差异。本研究旨在确定在一个年轻成人模拟样本中，精神疾病诊断与ASD特征之间的关联是否因性别而异。参与者（n = 84）为大学生，其ASD特征得分高于或低于预先确定的临界值。通过结构化精神科筛查访谈发现，与男性相比，ASD特征在女性中更能强烈预测超过情绪障碍的筛查阈值。文中讨论了未来的研究方向和临床意义。
