Rotzer A, Decurtins M, Largiadèr F
Helv Chir Acta. 1989 Dec;56(4):531-4.
During an 11-year period from 1978 to 1988, 720 cadaver kidneys were transplanted at the University Hospital of Zurich. 103 of the kidney grafts were from donors 16 years old or younger. The mean age of these donors was 11 years (range 2 1/3 to 16 years). There were 3 donors under 5 years, where we preserved and transplanted both kidneys en bloc. Only 3 recipients were less than 16 years old. After 1 year, 67 out of 103 recipients had a functioning pediatric graft. In the cyclosporine-treated group, the 1-year graft survival was even 80%, similar to kidney transplants from adult donors. Graft loss was observed in 48 cases. 33 patients rejected the transplant and 10 grafts were lost after recurrence of the primary renal disease. Only 5 grafts had a vascular complication. We conclude that kidneys from pediatric donors can successfully be transplanted into adults.
在1978年至1988年的11年期间，苏黎世大学医院共进行了720例尸体肾移植。其中103例肾移植物来自16岁及以下的供体。这些供体的平均年龄为11岁（范围为2又1/3岁至16岁）。有3名供体年龄在5岁以下，我们将其双肾整块保存并移植。只有3名受者年龄小于16岁。1年后，103名受者中有67人拥有功能良好的小儿移植物。在环孢素治疗组中，1年移植物存活率甚至达到80%，与成人供体肾移植相似。观察到48例移植物丢失。33例患者移植肾被排斥，10例移植物在原发性肾病复发后丢失。只有5例移植物出现血管并发症。我们得出结论，小儿供体的肾脏可以成功移植给成人。
