Yu Jessica, Fei Kezhen, Fox Ashley, Negron Rennie, Horowitz Carol
Institute for Health, Health Care Policy, and Aging Research, Rutgers - The State University of New Jersey, New Brunswick, NJ, United States; Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
Obes Res Clin Pract. 2016 May-Jun;10(3):283-90. doi: 10.1016/j.orcp.2015.07.010. Epub 2015 Aug 29.
The purpose of this study was to explore potential mediators of the relationship between depression and obesity in a sample of low-income, minority women. Data were extracted from a sample of 535 women enrolled in a weight loss intervention for the prevention of type 2 diabetes. Using a non-parametric bootstrapping procedure, the potential mediation effects of stress eating and sleep disturbance on the relationship between depression and obesity were tested. Results of a single mediation model indicated that depressive symptomatology was significantly associated with obesity (β=0.800, SE=0.290, p=0.006), and that stress eating (β=0.166, 95% CI [0.046, 0.328]) and sleep disturbance (β=1.032, 95% CI [0.612, 1.427]) were significant independent mediators of this relationship. Sleep disturbance remained a significant mediator in a combined mediation model (β=1.009, 95% CI [0.653, 1.399]). Findings add to the growing literature on the psychosocial factors implicated in the link between depression and obesity, particularly among disadvantaged populations. Future longitudinal research should aim to establish causal pathways between obesity, stress eating, sleep disturbance, and depression.
本研究的目的是在低收入少数族裔女性样本中探索抑郁症与肥胖症之间关系的潜在中介因素。数据取自535名参加预防2型糖尿病减肥干预项目的女性样本。采用非参数自抽样程序，测试了情绪化进食和睡眠障碍对抑郁症与肥胖症之间关系的潜在中介作用。单中介模型结果表明，抑郁症状与肥胖症显著相关（β=0.800，标准误=0.290，p=0.006），并且情绪化进食（β=0.166，95%置信区间[0.046, 0.328]）和睡眠障碍（β=1.032，95%置信区间[0.612, 1.427]）是这种关系的显著独立中介因素。在组合中介模型中，睡眠障碍仍然是一个显著的中介因素（β=1.009，95%置信区间[0.653, 1.399]）。研究结果为抑郁症与肥胖症之间联系所涉及的社会心理因素的文献增添了内容，特别是在弱势群体中。未来的纵向研究应旨在确立肥胖症、情绪化进食、睡眠障碍和抑郁症之间的因果路径。
