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本文引用的文献

1
Validity of midday total testosterone levels in older men with erectile dysfunction.午间总睾酮水平在老年勃起功能障碍男性中的有效性。
J Urol. 2014 Jul;192(1):165-9. doi: 10.1016/j.juro.2014.01.085. Epub 2014 Feb 8.
2
Testosterone therapy in men with androgen deficiency syndromes: an Endocrine Society clinical practice guideline.男性雄激素缺乏综合征的睾酮治疗:内分泌学会临床实践指南。
J Clin Endocrinol Metab. 2010 Jun;95(6):2536-59. doi: 10.1210/jc.2009-2354.
3
The effect of diurnal variation on clinical measurement of serum testosterone and other sex hormone levels in men.昼夜变化对男性血清睾酮及其他性激素水平临床测量的影响。
J Clin Endocrinol Metab. 2009 Mar;94(3):907-13. doi: 10.1210/jc.2008-1902. Epub 2008 Dec 16.
4
The association of time of day and serum testosterone concentration in a large screening population.大规模筛查人群中一天中的时间与血清睾酮浓度的关联。
BJU Int. 2007 Sep;100(3):509-13. doi: 10.1111/j.1464-410X.2007.07022.x. Epub 2007 Jun 6.
5
Circadian variation in serum free and non-SHBG-bound testosterone in normal men: measurements, and simulation using a mass action model.正常男性血清游离及非SHBG结合睾酮的昼夜变化:测量及基于质量作用模型的模拟
Clin Endocrinol (Oxf). 1993 Aug;39(2):163-71. doi: 10.1111/j.1365-2265.1993.tb01769.x.
6
Loss of circadian rhythmicity in blood testosterone levels with aging in normal men.正常男性随着年龄增长,血液睾酮水平的昼夜节律性丧失。
J Clin Endocrinol Metab. 1983 Jun;56(6):1278-81. doi: 10.1210/jcem-56-6-1278.

PURLS:是时候重新考虑清晨睾酮测试了。

PURLS: It's time to reconsider early-morning testosterone tests.

作者信息

Long Natalie, Nguyen Liz, Stevermer James

机构信息

Department of Family and Community Medicine, University of Missouri-Columbia, MO, USA.

University of Chicago, Department of Family Medicine, IL, USA.

出版信息

J Fam Pract. 2015 Jul;64(7):418-9.

PMID:26324959
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4501456/
Abstract

Guidelines recommend collecting an early-morning sample to compensate for the natural diurnal variation in testosterone levels. But for men 45 and older, this is unnecessary. Because the natural diurnal variation in testosterone levels tends to diminish with age, it is acceptable to test men ages 45 and older before 2 pm.

摘要

指南建议采集清晨样本,以补偿睾酮水平的自然昼夜变化。但对于45岁及以上的男性,这并无必要。由于睾酮水平的自然昼夜变化往往会随着年龄增长而减小,所以在下午2点之前对45岁及以上的男性进行检测是可以接受的。