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儿童鼻咽部肺炎球菌定植的患病率及携带菌株的抗菌药物敏感性谱。

Prevalence of nasopharyngeal pneumococcal colonization in children and antimicrobial susceptibility profiles of carriage isolates.

作者信息

Zhou Julie Y, Isaacson-Schmid Megan, Utterson Elizabeth C, Todd Elizabeth M, McFarland Michelle, Sivapalan Janardan, Niehoff Joan M, Burnham Carey-Ann D, Morley S Celeste

机构信息

Department of Pediatrics, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO, 63110.

Division of Gastroenterology, Hepatology and Nutrition, Washington University School of Medicine, St. Louis, MO, 63110.

出版信息

Int J Infect Dis. 2015 Oct;39:50-52. doi: 10.1016/j.ijid.2015.08.010. Epub 2015 Sep 3.

Abstract

Nasopharyngeal (NP) pneumococcal carriage predisposes children to pneumococcal infections. Defining the proportion of pneumococcal isolates that are antibiotic-resistant enables the appropriate choice of empiric therapies. The antibiogram of NP carriage isolates derived from a pediatric population following the introduction of the 13-valent pneumococcal conjugate vaccine was defined in this study.

摘要

鼻咽部肺炎球菌携带会使儿童易患肺炎球菌感染。确定耐药肺炎球菌分离株的比例有助于合理选择经验性治疗方法。本研究确定了在引入13价肺炎球菌结合疫苗后儿科人群鼻咽部携带分离株的抗菌谱。

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