Innos Kaire, Valvere Vahur, Padrik Peeter, Eelma Evelyn, Kütner Riina, Lehtsaar Jaak, Tekkel Mare
a Department of Epidemiology and Biostatistics , National Institute for Health Development , Tallinn , Estonia.
b Clinic of Oncology and Haematology , North Estonia Medical Centre , Tallinn , Estonia.
Women Health. 2016;56(2):129-40. doi: 10.1080/03630242.2015.1086468. Epub 2015 Sep 1.
The aim of this study was to examine past mammography use and mode of detection among breast cancer (BC) patients in Estonia, a country that has low screening coverage and high BC mortality. Women newly diagnosed with primary BC in Estonia in 2008-2010 were interviewed. Determinants of past mammography use and the detection of BC by mammography were studied using multivariate logistic regression. Among 977 participants, almost half reported no mammograms prior to the detection of BC. Overall, 22% of the cases were detected by mammography (16% by screening mammography). Detection by mammography was strongly related to age, past mammography use, and obesity. Among cases detected by mammography, 10% were stage III/IV at diagnosis (32% among cases detected by other modes). This study showed low mammography utilization and high rate of self-detection of BC in Estonia. Increased detection by mammography would help diagnose the disease at an earlier stage and consequently avoid premature BC deaths. Efforts should be undertaken to increase participation in screening and improve the availability of mammography among older and high-risk women. The results are likely to be relevant for other countries and population groups with low screening coverage.
本研究旨在调查爱沙尼亚乳腺癌(BC)患者过去的乳房X光检查使用情况及检测方式。爱沙尼亚是一个筛查覆盖率低且乳腺癌死亡率高的国家。对2008年至2010年在爱沙尼亚新诊断为原发性乳腺癌的女性进行了访谈。使用多变量逻辑回归研究过去乳房X光检查使用情况的决定因素以及通过乳房X光检查检测乳腺癌的情况。在977名参与者中,近一半报告在检测出乳腺癌之前未进行过乳房X光检查。总体而言,22%的病例是通过乳房X光检查发现的(16%是通过筛查乳房X光检查发现的)。通过乳房X光检查检测与年龄、过去的乳房X光检查使用情况以及肥胖密切相关。在通过乳房X光检查发现的病例中,10%在诊断时为III/IV期(在通过其他方式发现的病例中为32%)。本研究表明,爱沙尼亚乳房X光检查利用率低,乳腺癌自我检测率高。增加乳房X光检查检测有助于在疾病早期进行诊断,从而避免过早的乳腺癌死亡。应努力提高筛查参与率,并改善老年和高危女性乳房X光检查的可及性。这些结果可能与其他筛查覆盖率低的国家和人群相关。