Duprez D A, Standaert A M, Vertongen P T, De Pue N Y, Clement D L
Cardiology-Angiology, University Hospital, Gent, Belgium.
J Hypertens Suppl. 1989 Dec;7(6):S86-7. doi: 10.1097/00004872-198900076-00039.
It is not known whether there are vascular changes in the peripheral circulation of patients with orthostatic hypotension and patients with constitutional hypotension. Therefore, blood flow was studied simultaneously at the calf (mainly muscle circulation) and at the finger (mainly finger circulation) with ECG-triggered venous occlusion plethysmography. Calf and finger blood flow were measured for 20 min at rest and during reactive hyperaemia due to an arterial occlusion for 3 min. Vascular resistance was calculated from the blood flow and arterial blood pressure. In orthostatic hypotension there is a decreased vasodilator capacity of the calf resistance vessels and not of the finger resistance vessels. In constitutional hypotension there is a decreased vasodilator capacity of the calf and finger resistance vessels. These results suggest that there are structural or functional changes, or both, in the muscle and skin circulation of patients with constitutional hypotension, whereas there are only structural or functional changes, or both, in the muscle circulation of patients with orthostatic hypotension.
体位性低血压患者和体质性低血压患者的外周循环中是否存在血管变化尚不清楚。因此，采用心电图触发的静脉阻断体积描记法，同时研究了小腿（主要是肌肉循环）和手指（主要是手指循环）的血流情况。在静息状态下以及由于动脉阻塞3分钟引起的反应性充血期间，测量小腿和手指血流20分钟。根据血流和动脉血压计算血管阻力。在体位性低血压中，小腿阻力血管的血管舒张能力下降，而手指阻力血管的血管舒张能力未下降。在体质性低血压中，小腿和手指阻力血管的血管舒张能力均下降。这些结果表明，体质性低血压患者的肌肉和皮肤循环存在结构或功能变化，或两者皆有，而体位性低血压患者仅在肌肉循环中存在结构或功能变化，或两者皆有。
