Ludwig A, Van Ooteghem M
J Pharm Belg. 1989 Nov-Dec;44(6):391-7.
The influence of sodium hyaluronate and hydroxyethylcellulose on the elimination of a fluorescent tracer from the precorneal area of human eyes is investigated using a slit lamp fluorophotometer. The rheological characteristics of the equiviscous ophthalmic solutions are examined. Both viscosity enhancing polymers improve significantly the residence of the tracer in the tear film. The high viscous sodium hyaluronate solution is better tolerated than the hydroxyethylcellulose solution.
使用裂隙灯荧光光度计研究了透明质酸钠和羟乙基纤维素对人眼角膜前区荧光示踪剂消除的影响。检测了等粘性眼用溶液的流变学特性。两种增粘聚合物均显著改善了示踪剂在泪膜中的滞留时间。高粘性透明质酸钠溶液比羟乙基纤维素溶液耐受性更好。