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本文引用的文献

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Prostate specific antigen best practice statement: 2009 update.前列腺特异性抗原最佳实践声明：2009 年更新。
J Urol. 2013 Jan;189(1 Suppl):S2-S11. doi: 10.1016/j.juro.2012.11.014.
2
Informed prostate cancer risk-adjusted testing: a new paradigm.知情前列腺癌风险调整检测：一种新范式。
BJU Int. 2012 Dec;110 Suppl 4:30-4. doi: 10.1111/j.1464-410X.2012.11621.x.
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Risk-based prostate cancer screening.基于风险的前列腺癌筛查。
Eur Urol. 2012 Apr;61(4):652-61. doi: 10.1016/j.eururo.2011.11.029. Epub 2011 Nov 24.
4
Randomised prostate cancer screening trial: 20 year follow-up.随机前列腺癌筛查试验：20 年随访。
BMJ. 2011 Mar 31;342:d1539. doi: 10.1136/bmj.d1539.
5
EAU guidelines on prostate cancer. Part II: Treatment of advanced, relapsing, and castration-resistant prostate cancer.EAU 前列腺癌指南。第二部分：晚期、复发性和去势抵抗性前列腺癌的治疗。
Eur Urol. 2011 Apr;59(4):572-83. doi: 10.1016/j.eururo.2011.01.025. Epub 2011 Jan 25.
6
PSA-based prostate cancer screening: the role of active surveillance and informed and shared decision making.基于 PSA 的前列腺癌筛查：主动监测的作用以及知情和共同决策。
Asian J Androl. 2011 Mar;13(2):219-24. doi: 10.1038/aja.2010.180. Epub 2011 Feb 7.
7
Active surveillance compared with initial treatment for men with low-risk prostate cancer: a decision analysis.主动监测与初始治疗比较用于低危前列腺癌患者：决策分析。
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Use and assessment of PSA in prostate cancer.在前列腺癌中使用和评估 PSA。
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9
EAU guidelines on prostate cancer. Part 1: screening, diagnosis, and treatment of clinically localised disease.EAU 前列腺癌指南。第 1 部分：局限性疾病的筛查、诊断和治疗。
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前列腺特异性抗原应如何解读？

How should prostate specific antigen be interpreted?

作者信息

Atan Ali, Güzel Özer

机构信息

Department of Urology, Ankara Numune Training and Research Hospital, Ankara, Turkey.

出版信息

Turk J Urol. 2013 Sep;39(3):188-93. doi: 10.5152/tud.2013.038.

DOI:10.5152/tud.2013.038
PMID:26328106
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4548626/
Abstract

Since from its clinical introduction to the present time, measurement of serum prostate specific antigen (PSA) level is one of the most widely used tests in urology practice. Initially, the upper limit for PSA was 4 ng/mL, but today, a reduction for the upper limit is recommended to 2.5-3 ng/mL for patients between 60 and 65 years of age and younger. On the use of PSA as a screening test for prostate cancer, there are differences of opinion. However, it is a recommended test in the evaluation and monitoring of the risky group for prostate cancer. In conclusion PSA test should be performed at appropriate intervals for appropriate people with an appropriate age, after informing the patient about the test in detail.

摘要

自从血清前列腺特异性抗原（PSA）水平检测在临床上应用至今，它一直是泌尿外科实践中使用最广泛的检测方法之一。最初，PSA的上限值为4 ng/mL，但如今，对于60至65岁及以下的患者，建议将上限值降至2.5 - 3 ng/mL。关于将PSA用作前列腺癌筛查检测，存在不同意见。然而，在评估和监测前列腺癌风险人群时，它是一项推荐检测。总之，在向患者详细告知检测情况后，应针对合适年龄的合适人群，以适当的间隔进行PSA检测。