Şimşek Abdülmuttalip, Özgör Faruk, Akbulut Mehmet Fatih, Küçüktopçu Onur, Berberoğlu Ahmet Yalçın, Sarılar Ömer, Binbay Murat, Müslümanoğlu Ahmet Yaser
Department of Urology, Haseki Training and Research Hospital, İstanbul, Turkey.
Turk J Urol. 2014 Jun;40(2):104-9. doi: 10.5152/tud.2014.66674.
In obese patients, the management of renal calculi presents a number of challenges for urologists. In this study, we aimed to evaluate the efficacy and safety of percutaneous nephrolithotomy (PNL) procedure in obese and morbidly obese patients.
We retrospectively reviewed the medical files of 2360 patients treated with PNL between March 2002 and April 2013. The patients were stratified into four groups according to the World Health Organization (WHO) classification of body mass index (BMI): <25 kg/m(2) (average), 25-29.9 kg/m(2) (overweight), 30-39.9 kg/m(2) (obese), and >40 kg/m(2) (morbidly obese). Patients under 18 years of age and those with a body mass index under 18 kg/m(2) were excluded from the study. Intra-, and postoperative outcomes of PNL were compared between groups.
A total of 2102 patients with a mean age of 43±13.62 years were enrolled in the study. The mean stone size, mean number of stones, staghorn stone rate and history of previous shock wave lithotripsy were similar in all groups. The overall stone-free rate was 82 percent. The mean operation time was longer in the morbidly obese group but it was not significantly different from that in the other groups. No differences were observed in hospital stay, complication or stone-free rate among four study groups.
Percutaneous nephrolithotomy is a safe and effective treatment for renal stone disease. Body mass index does not affect the success or complication rate in PNL.
在肥胖患者中,肾结石的治疗给泌尿外科医生带来了诸多挑战。在本研究中,我们旨在评估经皮肾镜取石术(PNL)在肥胖和病态肥胖患者中的疗效及安全性。
我们回顾性分析了2002年3月至2013年4月间接受PNL治疗的2360例患者的病历。根据世界卫生组织(WHO)的体重指数(BMI)分类,将患者分为四组:<25 kg/m²(平均)、25 - 29.9 kg/m²(超重)、30 - 39.9 kg/m²(肥胖)和>40 kg/m²(病态肥胖)。18岁以下患者及BMI低于18 kg/m²的患者被排除在研究之外。比较各组PNL的术中及术后结果。
共有2102例平均年龄为43±13.62岁的患者纳入研究。所有组的平均结石大小、平均结石数量、鹿角形结石发生率及既往体外冲击波碎石史相似。总体无石率为82%。病态肥胖组的平均手术时间较长,但与其他组相比无显著差异。四个研究组在住院时间、并发症或无石率方面未观察到差异。
经皮肾镜取石术是治疗肾结石疾病的一种安全有效的方法。体重指数不影响PNL的成功率或并发症发生率。