Vujovic Aleksandra, Keoghane Stephen
St Mary's Hospital, Portsmouth, UK.
Nat Clin Pract Urol. 2007 Dec;4(12):671-6. doi: 10.1038/ncpuro0988.
Obesity represents an increasing burden to health care resources. Nephrolithiasis is associated with obesity and type 2 diabetes and the consumption of diets rich in protein, fat and carbohydrates; this article addresses some of the pathophysiological mechanisms associated with stone formation in these patients. Management of stone disease can be more difficult in obese patients; even diagnosis can be problematic because imaging techniques are less sensitive in these patients. Treatment with extracorporeal shockwave lithotripsy and surgery in obese patients can be challenging, and outcome data for the different treatments are discussed in this Review.
肥胖给医疗资源带来了日益沉重的负担。肾结石与肥胖、2型糖尿病以及富含蛋白质、脂肪和碳水化合物的饮食摄入有关;本文探讨了这些患者结石形成相关的一些病理生理机制。肥胖患者的结石病管理可能更困难;甚至诊断也可能存在问题,因为成像技术在这些患者中不太敏感。肥胖患者的体外冲击波碎石术和手术治疗可能具有挑战性,本综述讨论了不同治疗方法的结果数据。