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颅骨成形术的结果及相关并发症:一项单中心观察性研究。

Cranioplasty outcomes and associated complications: A single-centre observational study.

作者信息

Liang Ee Shern, Tipper Geoffrey, Hunt Lyn, Gan Peter Yee Chiung

机构信息

a Department of Neurosurgery , Waikato Hospital , Hamilton, Hamilton , New Zealand.

b Department of Statistics , Waikato University , Hamilton , New Zealand.

出版信息

Br J Neurosurg. 2016;30(1):122-7. doi: 10.3109/02688697.2015.1080216. Epub 2015 Aug 28.

Abstract

INTRODUCTION

The resurgence of decompressive craniectomy has led to recent published reviews of the safety of cranioplasties. To date there is a wide range of reported mortality and morbidity. This observational study reports the outcomes of the cranioplasty operations from a single centre and evaluates the factors involved in their management.

METHODS

A retrospective search of all theatre logs was performed for the years 2006-2013 inclusive. 88 operations were documented as 'Cranioplasty'. Data collection include patient demographics, type of cranioplasty used, time lapse between decompression and cranioplasty, seniority of the operating surgeon(s), antibiotic regimen and complications. Outcomes were recorded at the three-month follow-up.

RESULTS

The overall complication rate was 6.8%. The mean patient age was 36.2 years. 52.2% of patients had decompressive craniectomy for trauma, 11.3% had infectious pathology, 9% had subarachnoid haemorrhage, 9% had tumour with bone infiltration and 3.4% had stroke. 55.7% of patients had cranioplasty within 6 months of craniectomy. 61.3% of cranioplasties were with autologous bone, 20.4% titanium, 10.2% acrylic and 7.9% polyetheretherketone (PEEK). Significant complications included one case of infection, two cases of subgaleal haematoma and one extradural collection. No deaths were noted. No correlation was found between infection and the use of drains. 68.6% of cases were done by either a senior surgeon or a supervised registrar. There was an observable difference in complication rates in relation to the seniority and experience of the operator. However, patient numbers and complications were insufficient to achieve statistical significance. Strict antimicrobial prescribing was observed.

CONCLUSION

Some potentially preventable complications have been addressed with a resulting rate of complications lower than other published reports. We use two standard adjuncts: the presence of a senior surgeon and strict antimicrobial regimens. We believe that our results could be transferrable to other units by following similar guidelines.

摘要

引言

减压性颅骨切除术的再度兴起促使近期有关于颅骨修补术安全性的综述发表。迄今为止,报道的死亡率和发病率范围很广。这项观察性研究报告了来自单一中心的颅骨修补手术结果,并评估了其治疗过程中涉及的因素。

方法

对2006年至2013年(含)期间所有的手术记录进行回顾性检索。有88例手术记录为“颅骨修补术”。数据收集包括患者人口统计学资料、所使用的颅骨修补术类型、减压与颅骨修补之间的时间间隔、主刀医生的资历、抗生素治疗方案及并发症。在三个月随访时记录结果。

结果

总体并发症发生率为6.8%。患者平均年龄为36.2岁。52.2%的患者因创伤行减压性颅骨切除术,11.3%有感染性病变,9%有蛛网膜下腔出血,9%有骨浸润性肿瘤,3.4%有中风。55.7%的患者在颅骨切除术后6个月内进行了颅骨修补术。61.3%的颅骨修补使用自体骨,20.4%使用钛,10.2%使用丙烯酸,7.9%使用聚醚醚酮(PEEK)。严重并发症包括1例感染、2例帽状腱膜下血肿和1例硬膜外血肿。未发现死亡病例。未发现感染与引流管使用之间存在相关性。68.6%的病例由资深外科医生或带教住院医师完成。并发症发生率在与术者资历和经验相关方面存在可观察到的差异。然而,患者数量和并发症数量不足以达到统计学显著性。观察到严格的抗菌药物处方情况。

结论

一些潜在可预防的并发症已得到处理,并发症发生率低于其他已发表的报告。我们采用两个标准辅助措施:有资深外科医生在场和严格的抗菌治疗方案。我们认为,遵循类似指南,我们的结果可应用于其他科室。

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