Takemoto Y, Iriuchijima J
Department of Physiology, Faculty of Medicine, University of Hiroshima, Japan.
Jpn J Physiol. 1989;39(6):847-55. doi: 10.2170/jjphysiol.39.847.
Changes in regional blood flow and arterial pressure in the rat during spontaneous walk in a wheel were observed. An electromagnetic flow probe was implanted around the carotid, superior mesenteric, or renal artery, or the terminal aorta and a catheter for pressure measurement was inserted into the terminal aorta or the common carotid artery. The wheel had a diameter of 35 cm and rotated passively as the rat walked. When hindquarter (terminal aortic) flow increased markedly during wheel walk, carotid flow decreased, superior mesenteric flow decreased or remained unchanged, and renal flow did not change. Arterial pressure remained almost unchanged and heart rate increased an average of about 10%. Semiquantitative considerations indicated that arterial pressure was maintained in the face of the profuse increase in hindquarter flow during wheel walk by an increase in cardiac output rather than shifts of blood flow from other regions.
观察了大鼠在轮子上自发行走期间局部血流和动脉血压的变化。将电磁血流探头植入颈动脉、肠系膜上动脉、肾动脉或主动脉末端周围，并将用于压力测量的导管插入主动脉末端或颈总动脉。轮子直径为35厘米，当大鼠行走时被动旋转。在轮子行走期间，当后肢（主动脉末端）血流显著增加时，颈动脉血流减少，肠系膜上动脉血流减少或保持不变，肾血流没有变化。动脉血压几乎保持不变，心率平均增加约10%。半定量分析表明，在轮子行走期间后肢血流大量增加的情况下，动脉血压是通过心输出量增加而不是其他区域血流转移来维持的。
