Mizuma E, Takemoto Y, Iriuchijima J
Jpn J Physiol. 1987;37(1):49-57. doi: 10.2170/jjphysiol.37.49.
Changes in blood flow in the carotid, superior mesenteric, or renal artery or terminal aorta during grooming were measured in the conscious rat with a chronically implanted electromagnetic flow probe. Arterial pressure was measured simultaneously with an indwelling catheter. During grooming, carotid flow almost doubled and arterial pressure rose slightly, while hindquarter (terminal aortic) flow decreased by an average of about 20%. Superior mesenteric flow decreased occasionally and renal flow remained almost unchanged. Heart rate increased by an average of about 10%. An increase in carotid flow during grooming was similarly observed after cervical sympathectomy. After ganglion blockade with hexamethonium, grooming did not decrease hindquarter flow any more. These findings suggest that during grooming a substantial amount of blood flow is switched from the hindquarters to the carotid areas, to achieve a redistribution of cardiac output largely by excitation of the respective regional sympathetic and parasympathetic fibers and that sympathetic vasoconstrictor fibers supplying different vascular areas are controlled by separate pathways from separate neuron groups.
采用长期植入的电磁血流探头，在清醒大鼠梳理毛发期间测量其颈动脉、肠系膜上动脉、肾动脉或主动脉末端的血流变化。同时用留置导管测量动脉血压。在梳理毛发期间，颈动脉血流几乎增加一倍，动脉血压略有升高，而后肢（主动脉末端）血流平均减少约20%。肠系膜上动脉血流偶尔减少，肾血流几乎保持不变。心率平均增加约10%。颈部交感神经切除术后，梳理毛发时颈动脉血流同样增加。用六甲铵进行神经节阻断后，梳理毛发不再减少后肢血流。这些发现表明，在梳理毛发期间，大量血流从后肢转移至颈动脉区域，主要通过兴奋各自区域的交感和副交感纤维来实现心输出量的重新分配，并且供应不同血管区域的交感缩血管纤维由来自不同神经元群的独立通路控制。
