Timmermans Erik J, Schaap Laura A, Herbolsheimer Florian, Dennison Elaine M, Maggi Stefania, Pedersen Nancy L, Castell Maria Victoria, Denkinger Michael D, Edwards Mark H, Limongi Federica, Sánchez-Martínez Mercedes, Siviero Paola, Queipo Rocio, Peter Richard, van der Pas Suzan, Deeg Dorly J H
J Rheumatol. 2015 Oct;42(10):1885-92. doi: 10.3899/jrheum.141594. Epub 2015 Sep 1.
This study examined whether daily weather conditions, 3-day average weather conditions, and changes in weather conditions influence joint pain in older people with osteoarthritis (OA) in 6 European countries.
Data from the population-based European Project on OSteoArthritis were used. The American College of Rheumatology classification criteria were used to diagnose OA in older people (65-85 yrs). After the baseline interview, at 6 months, and after the 12-18 months followup interview, joint pain was assessed using 2-week pain calendars. Daily values for temperature, precipitation, atmospheric pressure, relative humidity, and wind speed were obtained from local weather stations. Multilevel regression modelling was used to examine the pain-weather associations, adjusted for several confounders.
The study included 810 participants with OA in the knee, hand, and/or hip. After adjustment, there were significant associations of joint pain with daily average humidity (B = 0.004, p < 0.01) and 3-day average humidity (B = 0.004, p = 0.01). A significant interaction effect was found between daily average humidity and temperature on joint pain. The effect of humidity on pain was stronger in relatively cold weather conditions. Changes in weather variables between 2 consecutive days were not significantly associated with reported joint pain.
The associations between pain and daily average weather conditions suggest that a causal relationship exist between joint pain and weather variables, but the associations between day-to-day weather changes and pain do not confirm causation. Knowledge about the relationship between joint pain in OA and weather may help individuals with OA, physicians, and therapists to better understand and manage fluctuations in pain.
本研究调查了6个欧洲国家中,每日天气状况、3天平均天气状况以及天气变化是否会影响老年骨关节炎(OA)患者的关节疼痛。
使用了基于人群的欧洲骨关节炎项目的数据。采用美国风湿病学会分类标准诊断老年人(65 - 85岁)的OA。在基线访谈后、6个月时以及12 - 18个月的随访访谈后,使用为期2周的疼痛日历评估关节疼痛。每日的温度、降水量、气压、相对湿度和风速值从当地气象站获取。采用多水平回归模型来研究疼痛与天气的关联,并对多个混杂因素进行了调整。
该研究纳入了810名膝、手和/或髋关节OA患者。调整后,关节疼痛与每日平均湿度(B = 0.004,p < 0.01)和3天平均湿度(B = 0.004,p = 0.01)存在显著关联。发现每日平均湿度和温度对关节疼痛有显著的交互作用。在相对寒冷的天气条件下,湿度对疼痛的影响更强。连续两天天气变量的变化与报告的关节疼痛无显著关联。
疼痛与每日平均天气状况之间的关联表明关节疼痛与天气变量之间存在因果关系,但每日天气变化与疼痛之间的关联并不能证实因果关系。了解OA关节疼痛与天气之间的关系可能有助于OA患者、医生和治疗师更好地理解和管理疼痛波动。