Research Institute of Orthopaedics & Traumatology, Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, P.R. China.
Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, P.R. China.
Ann Med. 2023 Dec;55(1):2196439. doi: 10.1080/07853890.2023.2196439.
Although there is an assertion that weather conditions affect osteoarthritis (OA) pain, the results from clinical studies remain inconsistent. This meta-analysis was performed to evaluate the association between weather conditions and OA pain.
Cochrane Library, Embase, PubMed, and Web of Science were searched from inception to September 30, 2022. Observational studies that explored all weather conditions associated with pain intensity were included. In the systematic review, the methodological quality of the selected studies was assessed and a best-evidence synthesis was used to make qualitative conclusions. Based on homogeneous results, Fisher's scores derived from the effect size of temperature (T), barometric pressure (BP) or relative humidity (RH) related to OA pain were synthesized and further transformed to the correlation coefficients (summary r) in meta-analysis.
A total of 14 studies were included in the best-evidence synthesis of a qualitative systematic review. There was strong evidence with 13 of 14 studies reporting consistent findings that weather factors in general, including any kind of meteorological condition, were associated with OA pain. Subsequently, 3 studies regarding BP or T, and 5 studies regarding RH with the pain of OA were included in quantitative meta-analyses. Both BP (pooled Fisher's = 0.37, 95% CI 0.15 to 0.59; summary = 0.35, 95% CI 0.15 to 0.53) and RH (pooled Fisher's = 0.10, 95% CI 0.01 to 0.18; summary = 0.086, 95% CI -0.05 to 0.22) were positively related to OA pain, while T was negatively related to OA pain (pooled Fisher's = -0.38, 95% CI -0.60 to -0.16; summary = -0.36, 95% CI -0.54 to -0.16).
In this study, weather factors in general were significantly associated with OA pain. It may provide useful references for the daily health management of OA. More studies designed with the consistent meteorological condition are warranted to validate the findings.KEY MESSAGEMany people with osteoarthritis think their joint pain is affected by the weather, while the association between OA pain and weather conditions is still unclear.This is a systematic review and meta-analysis of 14 observational studies for the association between weather conditions and OA pain.Weather conditions appear to be associated with OA pain. Barometric pressure and relative humidity were positively correlated to OA pain intensity, while temperature was negatively correlated to OA pain.
尽管有人断言天气条件会影响骨关节炎（OA）疼痛，但临床研究的结果仍不一致。本荟萃分析旨在评估天气条件与 OA 疼痛之间的关系。
从建库到 2022 年 9 月 30 日，检索 Cochrane 图书馆、Embase、PubMed 和 Web of Science，纳入所有与疼痛强度相关的天气条件的观察性研究。在系统评价中，评估了所选研究的方法学质量，并使用最佳证据综合法做出定性结论。基于同质结果，从与 OA 疼痛相关的温度（T）、气压（BP）或相对湿度（RH）的效应大小得出 Fisher 得分，并进一步转换为荟萃分析中的相关系数（汇总 r）。
共有 14 项研究纳入定性系统评价的最佳证据综合。其中 13 项研究均有强有力的证据表明，一般天气因素，包括任何气象条件，都与 OA 疼痛有关。随后，纳入了 3 项关于 BP 或 T 的研究，5 项关于 RH 与 OA 疼痛的研究进行定量荟萃分析。BP（汇总 Fisher's = 0.37，95%CI 0.15 至 0.59；汇总 r = 0.35，95%CI 0.15 至 0.53）和 RH（汇总 Fisher's = 0.10，95%CI 0.01 至 0.18；汇总 r = 0.086，95%CI -0.05 至 0.22）与 OA 疼痛呈正相关，而 T 与 OA 疼痛呈负相关（汇总 Fisher's = -0.38，95%CI -0.60 至 -0.16；汇总 r = -0.36，95%CI -0.54 至 -0.16）。
本研究表明，一般天气因素与 OA 疼痛明显相关。这可能为 OA 的日常健康管理提供有用的参考。需要更多设计一致气象条件的研究来验证这些发现。
许多骨关节炎患者认为他们的关节疼痛受天气影响，而 OA 疼痛与天气条件之间的关系仍不清楚。这是一项系统评价和荟萃分析，共纳入 14 项观察性研究，探讨天气条件与 OA 疼痛之间的关系。天气条件似乎与 OA 疼痛有关。气压和相对湿度与 OA 疼痛强度呈正相关，而温度与 OA 疼痛呈负相关。
