与不宁腿综合征/威利-埃克博姆病共存。
Living with Restless Legs Syndrome/Willis-Ekbom Disease.
作者信息
Tachibana Naoko
机构信息
Center for Sleep-related Disorders, Kansai Electric Power Hospital, 2-1-7 Fukushima, Fukushima, Osaka 553-0003, Japan.
出版信息
Sleep Med Clin. 2015 Sep;10(3):359-67, xv. doi: 10.1016/j.jsmc.2015.05.019. Epub 2015 Jul 2.
Restless legs syndrome/Willis-Ekbom disease (RLS/WED) is commonly seen in patients with end-stage renal disease (ESRD), but this condition has not been properly recognized. The prevalence of RLS/WED in ESRD shows the ethnic variation (7%-68%), with the similar tendency of primary RLS/WED. Although RLS/WED in ESRD is defined in secondary RLS/WED, the factors of ESRD that are involved in the genesis of RLS/WED remain unknown. Even after renal transplantation, RLS/WED symptoms do not completely disappear, and genetic predisposition to RLS/WED may play an important role in causing RLS/WED. Long-term intervention for RLS/WED and ESRD will be necessary.
不宁腿综合征/威利-埃克博姆病（RLS/WED）在终末期肾病（ESRD）患者中很常见，但这种情况尚未得到充分认识。ESRD中RLS/WED的患病率存在种族差异（7%-68%），与原发性RLS/WED有相似趋势。虽然ESRD中的RLS/WED被定义为继发性RLS/WED，但ESRD中参与RLS/WED发病的因素仍不清楚。即使在肾移植后，RLS/WED症状也不会完全消失，RLS/WED的遗传易感性可能在导致RLS/WED方面起重要作用。对RLS/WED和ESRD进行长期干预将是必要的。
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