Hadanny Amir, Efrati Shai
Sagol Center for Hyperbaric Medicine and Research, Assaf Harofeh Medical Center, Zerifin, 70300, Israel.
Sackler School of Medicine, Tel-Aviv University, Klachkin 25, Tel Aviv, 69978, Israel.
Crit Care. 2015 Sep 1;19(1):307. doi: 10.1186/s13054-015-1034-2.
Effective brain metabolism is highly dependent on a narrow therapeutic window of oxygen. In major insults to the brain (e.g., intracerebral hemorrhage), a slight decrease in oxygen supply, as occurs in a hypobaric environment at high altitude, has devastating effects on the injured brain tissue. Conversely, increasing brain oxygenation, by the use of hyperbaric oxygen therapy, can improve brain metabolism and its dependent regenerative processes.
有效的脑代谢高度依赖于狭窄的氧治疗窗。在对大脑的严重损伤(如脑出血)中,氧气供应的轻微减少,就像在高海拔的低压环境中发生的那样,会对受损的脑组织产生毁灭性影响。相反,通过使用高压氧疗法增加脑氧合,可以改善脑代谢及其相关的再生过程。