Wang K Y, Chan K H, Lee M C, Ma J Y, Lee Y H, Lee T Y, Chen M T
Ma Zui Xue Za Zhi. 1989 Dec;27(4):341-8.
Two hundred patients undergoing shock wave lithotripsy for renal calculi with the improved version of Dornier HM3 lithotripter system were randomly divided into group A and group B with 100 patients in each. Patients in group A were orally given tramadol 100 mg and lorazepam 1 mg and those in group B flunitrazepam 1 mg was given. Those in group A, who did not need supplemental medication during ESWL were subdivided in group A while those who needed an adjuvant of 100 micrograms intravenous fentanyl were subdivided in group A2. Like group A, those in group B, who did not need supplemental drug and those who needed 100 micrograms intravenous fentanyl were respectively subcategorized into groups B1 and B2. Drugs were given with 15 mL water 30 min prior to ESWL. Pre-operatively, an intravenous line and monitoring system which included noninvasive blood pressure and pulse oximeter were established. The entire course was divided into 5 stages i.e. stage I (prior to oral medication), stage II (10 min after medication), stage III (10 min following ESWL), stage IV (5 min following 100 micrograms intravenous fentanyl) and stage V (10 min after ESWL). The mean blood pressure, heart rate and SpO2, pain scale, sedation scale and side effects were recorded in various stages. The results showed that in group A 68 patients passed the ESWL smoothly (A1) and 32 patients needed supplemental fentanyl (A2). In group B 70 patients successfully underwent the ESWL (B1) while 30 patients needed supplemental fentanyl (B2). Ther were no significant changes in both groups in various stages regarding heart rate.(ABSTRACT TRUNCATED AT 250 WORDS)
200例使用改进版多尼尔HM3碎石系统进行肾结石冲击波碎石术的患者被随机分为A组和B组，每组100例。A组患者口服100毫克曲马多和1毫克劳拉西泮，B组患者给予1毫克氟硝西泮。A组中，在体外冲击波碎石术（ESWL）期间不需要补充药物的患者被细分为A1组，而需要100微克静脉注射芬太尼辅助药物的患者被细分为A2组。与A组一样，B组中不需要补充药物的患者和需要100微克静脉注射芬太尼的患者分别被归类为B1组和B2组。在ESWL前30分钟用15毫升水送服药物。术前，建立静脉通路和监测系统，包括无创血压和脉搏血氧仪。整个过程分为5个阶段，即阶段I（口服药物前）、阶段II（服药后10分钟）、阶段III（ESWL后10分钟）、阶段IV（静脉注射100微克芬太尼后5分钟）和阶段V（ESWL后10分钟）。记录各阶段的平均血压、心率、血氧饱和度、疼痛评分、镇静评分和副作用。结果显示，A组68例患者顺利通过ESWL（A1），32例患者需要补充芬太尼（A2）。B组70例患者成功接受ESWL（B1），30例患者需要补充芬太尼（B2）。两组在各阶段心率均无显著变化。（摘要截短至250字）
