Meurk Carla, Fraser Doug, Weier Megan, Lucke Jayne, Carter Adrian, Hall Wayne
UQ Centre for Clinical Research, Royal Brisbane and Women's Hospital Site, University of Queensland, Brisbane, Australia.
Faculty of Health and Behavioural Sciences, Centre for Youth Substance Abuse Research, The University of Queensland, Brisbane, Australia.
Drug Alcohol Rev. 2016 Jul;35(4):461-9. doi: 10.1111/dar.12318. Epub 2015 Aug 31.
The brain disease model of addiction posits that addiction is a persistent form of neural dysfunction produced by chronic drug use, which makes it difficult for addicted persons to become and remain abstinent. As part of an anticipatory policy analysis of addiction neuroscience, we engaged family members of addicted individuals to assess their views on the place and utility of brain-based accounts of addiction.
Fifteen in-depth qualitative interviews were conducted and used to develop a quantitative online survey that was completed by 55 family members. This article reports responses on what addiction is and how it is caused and responses to explanations of the brain disease model of addiction.
Participants gave multiple reasons for their family members developing an addiction and there was no single dominant belief about the best way to describe addiction. Participants emphasised the importance of both scientific and non-scientific perspectives on addiction by providing multifactorial explanations of their family members' addictions. Most family members acknowledged that repeated drug use can cause changes to the brain, but they varied in their reactions to labelling addiction a 'brain disease'. They believed that understanding addiction, and how it is caused, could help them support their addicted relative.
Participants' beliefs about neurobiological information and the brain disease model of addiction appeared to be driven by empathetic, utilitarian considerations rather than rationalist ones. We discuss the importance of providing information about the nature and causes of addiction. [Meurk C, Fraser D, Weier M, Lucke J, Carter A, Hall W. Assessing the place of neurobiological explanations in accounts of a family member's addiction. Drug Alcohol Rev 2016;35:461-469].
成瘾的脑疾病模型认为,成瘾是慢性药物使用导致的一种持续的神经功能障碍形式,这使得成瘾者难以实现并保持戒断状态。作为成瘾神经科学预期政策分析的一部分,我们邀请成瘾个体的家庭成员评估他们对基于大脑的成瘾解释的地位和效用的看法。
进行了15次深入的定性访谈,并据此开发了一项定量在线调查,由55名家庭成员完成。本文报告了关于成瘾是什么、成瘾如何产生的回答,以及对成瘾脑疾病模型解释的回应。
参与者给出了其家庭成员成瘾的多种原因,对于描述成瘾的最佳方式没有单一的主导观点。参与者通过对其家庭成员成瘾提供多因素解释,强调了成瘾的科学和非科学观点的重要性。大多数家庭成员承认反复使用药物会导致大脑变化,但他们对将成瘾称为“脑疾病”的反应各不相同。他们认为了解成瘾及其成因有助于他们支持成瘾的亲属。
参与者对神经生物学信息和成瘾脑疾病模型的看法似乎是由同理心、功利性考虑而非理性主义考虑驱动的。我们讨论了提供关于成瘾本质和成因信息的重要性。[默克C,弗雷泽D,韦尔M,卢克J,卡特A,霍尔W。评估神经生物学解释在家庭成员成瘾描述中的地位。《药物与酒精评论》2016年;35:461 - 469]