Hennion Sophie, Szurhaj William, Duhamel Alain, Lopes Renaud, Tyvaert Louise, Derambure Philippe, Delbeuck Xavier
a Epilepsy Unit, Department of Clinical Neurophysiology , Lille University Medical Center , Lille , France.
J Clin Exp Neuropsychol. 2015;37(9):931-45. doi: 10.1080/13803395.2015.1068280.
The present study sought to characterize and predict the recognition of emotional stimuli (presented in a visual or auditory modality) by patients with temporal lobe epilepsy (TLE).
Fifty TLE patients and 50 matched controls performed two emotion recognition tasks (emotional faces and emotional bursts). Neutral stimuli were also presented, and emotional biases were monitored by analyzing errors. Demographic, cognitive, psychobehavioral and (in TLE patients only) clinical and quality of life data were also recorded.
Compared with controls, TLE patients were impaired in the recognition of fear expressions in both visual and auditory modality tasks. However, impairments in the two channels were not always concomitant on the individual level. In the visual modality, recognition of disgust and neutral expressions was significantly worse in TLE patients. In the auditory modality, nonsignificant trends toward poor recognition of disgust and neutral expressions were observed. Negative biases were noted in TLE patients; expressions of fear (faces and bursts) were more frequently misinterpreted as disgust, and neutral facial expressions were more frequently misinterpreted as sadness. Impairments in the recognition of facial fear were less pronounced in left TLE patients who (according to structural magnetic resonance imaging, MRI) did not have any brain lesions. In TLE patients, low levels of social support (a quality of life parameter) were associated with worse recognition of facial disgust, and higher levels of apathy were associated with better recognition of neutral faces.
TLE patients are impaired in some aspects of emotion recognition with both visual and auditory stimuli, although the differential impact of TLE on these modalities requires further research. These emotional impairments are related to quality of life and psychobehavioral parameters.
本研究旨在对颞叶癫痫（TLE）患者识别情绪刺激（以视觉或听觉形式呈现）的情况进行特征描述和预测。
50名TLE患者和50名匹配的对照者完成两项情绪识别任务（情绪面孔和情绪爆发音）。同时也呈现中性刺激，通过分析错误情况来监测情绪偏差。还记录了人口统计学、认知、心理行为以及（仅在TLE患者中）临床和生活质量数据。
与对照者相比，TLE患者在视觉和听觉形式任务中识别恐惧表情的能力均受损。然而，在个体水平上，两个通道的损伤并不总是同时出现。在视觉形式中，TLE患者识别厌恶和中性表情的能力明显更差。在听觉形式中，观察到识别厌恶和中性表情能力较差的趋势，但不显著。TLE患者存在负性偏差；恐惧表情（面孔和爆发音）更频繁地被误判为厌恶，中性面部表情更频繁地被误判为悲伤。根据结构磁共振成像（MRI）显示没有任何脑损伤的左侧TLE患者，对面部恐惧的识别损伤不太明显。在TLE患者中，低水平的社会支持（生活质量参数）与面部厌恶识别能力较差相关，而较高水平的冷漠与中性面孔识别能力较好相关。
TLE患者在视觉和听觉刺激的情绪识别某些方面存在损伤，尽管TLE对这些形式的不同影响需要进一步研究。这些情绪损伤与生活质量和心理行为参数相关。
