Hennion Sophie, Sequeira Henrique, D'Hondt Fabien, Duhamel Alain, Lopes Renaud, Tyvaert Louise, Derambure Philippe, Szurhaj William, Delbeuck Xavier
Epilepsy Unit, Department of Clinical Neurophysiology, Lille University Medical Center, Lille, France; EA 1046 Vascular and Degenerative Cognitive Disorders Research Unit, Lille North of France University, Lille, France.
EA 4559 Laboratory of Functional Neurosciences and Pathologies, Lille North of France University, Lille, France.
Epilepsy Behav. 2015 Apr;45:15-20. doi: 10.1016/j.yebeh.2015.02.005. Epub 2015 Mar 17.
The objectives of the present study were to (i) better characterize visual emotional experience in patients with temporal lobe epilepsy (TLE), (ii) identify clinical risk factors that might be predictive of a change in emotional experience, and (iii) study the relationships between emotional experience and psychobehavioral/quality-of-life factors. Fifty patients with TLE and fifty matched controls evaluated the emotional content of unpleasant, pleasant, and neutral pictures with respect to their valence (unpleasant-to-pleasant) and arousal (low-to-high) levels. Demographic, cognitive, and psychobehavioral data were recorded for all participants, and clinical data and factors related to quality of life were also collected for patients with TLE. There were no significant differences between the group with TLE and the control group in terms of valence evaluations. However, arousal scores for neutral pictures were significantly higher in patients with TLE than in controls. There was also a nonsignificant trend towards lower arousal scores for pleasant pictures in patients with TLE than in controls. Although none of the recorded clinical factors were found to be related to emotional experience, the level of apathy was predictive of greater arousal experience for neutral pictures in patients with TLE. In conclusion, emotional experience appears to be modified in TLE and might be related to apathy. Changes in emotional experience should be taken into account in studies in which neutral stimuli are used to establish a baseline level when assessing emotional and cognitive processing.
（i）更好地描述颞叶癫痫（TLE）患者的视觉情绪体验；（ii）确定可能预测情绪体验变化的临床风险因素；（iii）研究情绪体验与心理行为/生活质量因素之间的关系。50名TLE患者和50名匹配的对照者对不愉快、愉快和中性图片的情绪内容在效价（从不愉快到愉快）和唤醒度（从低到高）水平方面进行了评估。记录了所有参与者的人口统计学、认知和心理行为数据，同时也收集了TLE患者的临床数据和与生活质量相关的因素。TLE组和对照组在效价评估方面没有显著差异。然而，TLE患者中性图片的唤醒度得分显著高于对照组。TLE患者愉快图片的唤醒度得分也有低于对照组的不显著趋势。虽然所记录的临床因素均未发现与情绪体验有关，但冷漠程度可预测TLE患者中性图片有更高的唤醒体验。总之，情绪体验在TLE中似乎发生了改变，且可能与冷漠有关。在使用中性刺激来建立评估情绪和认知加工的基线水平的研究中，应考虑情绪体验的变化。
