Akdeniz Gülsüm, Gumusyayla Sadiye, Vural Gonul, Deniz Orhan, Özışık Pınar
Department of Biophysics, Department of Neuroscience, Faculty of Medicine, Ankara Yildirim Beyazit University, and Yenimahalle Training and Research Hospital, Ankara, 06018, Turkey.
Department of Neurology, Faculty of Medicine, Ankara Yildirim Beyazit University, Ankara, 06801, Turkey.
Acta Epileptol. 2024 Oct 9;6(1):34. doi: 10.1186/s42494-024-00175-2.
Visual perception of face images or face pareidolia can be evaluated with event-related potentials (ERP) for healthy subjects and patients with neurological conditions. In this study, we aimed to analyse event-related potential components such as P100, N100, N170, and vertex-positive potential (VPP) in response to face pareidolia perception in temporal lobe epilepsy (TLE) patients.
ERPs were recorded during the pareidolia test. Waveforms were analzyed and current source density (CSD) maps were generated.
CSD profiles were shown to be interpretable when face and face pareidolia conditions. N100, P100, and N170 components showed larger amplitudes and longer latency in epilepsy patients in response to face pareidolia stimuli compared to real face images. However, the N170 component latency did not differ significantly between epilepsy patients and healthy participants, while the larger amplitude and longer latency of N100 and P100 responses were evoked in healthy patients.
Our results indicate a difference in the neural mechanisms of processing real face information and pareidolia face-like information in TLE patients.
对于健康受试者和患有神经系统疾病的患者，可通过事件相关电位（ERP）来评估对面部图像的视觉感知或面部空想性错视。在本研究中，我们旨在分析颞叶癫痫（TLE）患者在对面部空想性错视感知时的事件相关电位成分，如P100、N100、N170和顶点正电位（VPP）。
在空想性错视测试期间记录ERP。分析波形并生成电流源密度（CSD）图。
当处于面部和面部空想性错视条件时，CSD分布图是可解释的。与真实面部图像相比，癫痫患者在面对面部空想性错视刺激时，N100、P100和N170成分显示出更大的振幅和更长的潜伏期。然而，癫痫患者和健康参与者之间的N170成分潜伏期没有显著差异，而健康患者诱发的N100和P100反应具有更大的振幅和更长的潜伏期。
我们的结果表明，TLE患者在处理真实面部信息和空想性错视面部样信息的神经机制上存在差异。
