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[慢性胰腺炎中胰酶微丸与胰酶片的比较性交叉研究]

[A comparative cross-over study of pellet pancreatin and tablet pancreatin in chronic pancreatitis].

作者信息

Herrerías J M, Gómez Parra M, García Montes J M, Petit M A, Valladolid León J M

出版信息

Rev Esp Enferm Apar Dig. 1989 Dec;76(6 Pt 2):651-3.

PMID:2633238
Abstract

We have made a comparative cross study of 30 patients with chronic pancreatitis and steatorrhea. The aim of the study has been to compare the effectiveness of a new galenic form of pancreatin, in pellets, with the common galenic presentation, in tablets. In all the cases the cause of pancreatic failure was alcoholism. In both groups the treatment was administered during seven days, after a period of wash out. We evaluated steatorrhea and clinical symptoms, including the typical abdominal pain. (The doses administrated were 12 tablets/day or 9 pellets/day.) Statistically there was a significant decrease of steatorrhea p less than 0.01.

摘要

我们对30例慢性胰腺炎伴脂肪泻患者进行了一项对比交叉研究。该研究的目的是比较一种新的丸剂形式的胰酶与普通片剂形式的疗效。所有病例中胰腺功能不全的病因均为酒精中毒。两组均在洗脱期后进行为期7天的治疗。我们评估了脂肪泻和临床症状,包括典型的腹痛。(给药剂量为每日12片或每日9粒丸剂。)统计学上,脂肪泻有显著下降,p值小于0.01。

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