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[索拉西与非特异性慢性喉炎]

[Solacy and non-specific chronic laryngitis].

作者信息

Berezin A

出版信息

Rev Laryngol Otol Rhinol (Bord). 1989;110(5):525-8.

PMID:2633259
Abstract

Adult subjects, without age or sex distinction, presenting a non-specific chronic laryngitis were treated with SOLACY. The posology of SOLACY administered was: 2 capsules in the morning and 2 at night for four months in a row. The subjects were seen at least twice: one consultation before the treatment and one after the 4 months of treatment. These consultations included an interview and fibroscopic test of the laryngeal mucosa (photographs were taken). The subjects were also requested to quantify the overall discomfort experienced. Ten subjects were recruited for this study. Dysphonia was significantly lower after the 4-month treatment as was the self-evaluation of the overall discomfort brought on by the different symptoms. In addition, it can be noted that SOLACY lessened coughing and laryngeal discomfort in most of the patients treated and it improved the fibroscopic test results, especially concerning the congestive aspect of the laryngeal mucosa, whether limited to vocal chords or spread throughout the entire vestibule. The treatment was tolerated perfectly well. In conclusion, SOLACY, administered in adults presenting non-specific chronic laryngitis improves the state of the laryngeal mucosa and its main symptoms (dysphonia, coughing, laryngeal discomfort).

摘要

成年受试者,不分年龄和性别,患有非特异性慢性喉炎,接受索拉西治疗。索拉西的用药剂量为:连续四个月,每天早上2粒胶囊,晚上2粒胶囊。受试者至少接受两次检查:治疗前一次会诊,治疗四个月后一次会诊。这些会诊包括访谈和喉部黏膜纤维镜检查(拍摄照片)。还要求受试者对所经历的总体不适进行量化。本研究招募了10名受试者。经过4个月的治疗后,发声困难明显减轻,不同症状引起的总体不适的自我评估也有所减轻。此外,可以注意到,索拉西减轻了大多数接受治疗患者的咳嗽和喉部不适,并改善了纤维镜检查结果,特别是关于喉部黏膜充血方面,无论是局限于声带还是蔓延至整个前庭。该治疗耐受性良好。总之,对患有非特异性慢性喉炎的成年人使用索拉西可改善喉部黏膜状态及其主要症状(发声困难、咳嗽、喉部不适)。

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