全髋关节和膝关节置换术后预防金黄色葡萄球菌手术部位感染的筛查与去定植现状
The Current State of Screening and Decolonization for the Prevention of Staphylococcus aureus Surgical Site Infection After Total Hip and Knee Arthroplasty.
作者信息
Weiser Mitchell C, Moucha Calin S
机构信息
Department of Orthopaedics, Icahn School of Medicine at Mount Sinai, 5 East 98th Street, 9th Floor, Box 1188, New York, NY 10029. E-mail address for M.C. Weiser:
出版信息
J Bone Joint Surg Am. 2015 Sep 2;97(17):1449-58. doi: 10.2106/JBJS.N.01114.
Abstract
The most common pathogens in surgical site infections after total hip and knee arthroplasty are methicillin-sensitive Staphylococcus aureus (MSSA), methicillin-resistant S. aureus (MRSA), and coagulase-negative staphylococci. Patients colonized with MSSA or MRSA have an increased risk for a staphylococcal infection at the site of a total hip or knee arthroplasty. Most colonized individuals who develop a staphylococcal infection at the site of a total hip or total knee arthroplasty have molecularly identical S. aureus isolates in their nares and wounds. Screening and nasal decolonization of S. aureus can potentially reduce the rates of staphylococcal surgical site infection after total hip and total knee arthroplasty.
摘要
全髋关节和膝关节置换术后手术部位感染最常见的病原体是甲氧西林敏感金黄色葡萄球菌（MSSA）、耐甲氧西林金黄色葡萄球菌（MRSA）和凝固酶阴性葡萄球菌。携带MSSA或MRSA的患者在全髋关节或膝关节置换部位发生葡萄球菌感染的风险增加。大多数在全髋关节或全膝关节置换部位发生葡萄球菌感染的定植个体，其鼻腔和伤口中的金黄色葡萄球菌分离株在分子水平上是相同的。对金黄色葡萄球菌进行筛查和鼻腔去定植可能会降低全髋关节和全膝关节置换术后葡萄球菌手术部位感染的发生率。
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