波兰美沙酮维持治疗患者的躯体合并症及与自杀未遂相关的其他因素
Somatic Comorbidity and Other Factors Related to Suicide Attempt Among Polish Methadone Maintenance Patients.
作者信息
Fudalej Sylwia, Ilgen Mark, Kołodziejczyk Iwona, Podgórska Anna, Serafin Piotr, Barry Kristen, Wojnar Marcin, Blow Frederic C, Bohnert Amy
机构信息
Department of Psychiatry (S.F., A.P., M.W.), Medical University of Warsaw, Warsaw, Poland; Department of Psychiatry (M.I., K.B., M.W., F.C.B., A.B.), University of Michigan, Ann Arbor, MI, USA; Department of Veterans Affairs (M.I., K.B., F.C.B., A.B.), Center for Clinical Management Research, Ann Arbor, MI, USA; and Nowowiejski Hospital (I.K., P.S.), Warsaw, Poland.
出版信息
J Addict Med. 2015 Nov-Dec;9(6):433-9. doi: 10.1097/ADM.0000000000000153.
OBJECTIVES
Fatal and nonfatal suicide attempts are far more common in opioid-dependent individuals than in the general population. More research is needed to understand the specific risk factors for suicidal behaviors in this patient population, particularly outside of the United States and Western Europe. This study investigated the correlates of suicide attempts among Polish patients in methadone maintenance treatment and interpreted results in the context of findings from other countries.
METHODS
The study was based on a sample of 240 individuals recruited from a methadone maintenance clinic in Poland. Participants were interviewed using standardized measures.
RESULTS
Consistent with studies in other countries, sexual abuse, depression, alcohol dependence, and impulsivity were associated with suicide attempt. Additionally, those patients with somatic comorbidity had an increase in odds (odds ratio = 2.6) of suicide attempt.
CONCLUSIONS
The results of our study suggest a potential benefit to treatment approaches that address somatic concerns of methadone-maintenance patients. More research is needed to identify, assess, and understand possible cultural and regional differences between opioid-dependent populations to better tailor prevention strategies.
目的
与普通人群相比，阿片类药物依赖者的致命和非致命自杀未遂情况更为常见。需要开展更多研究以了解该患者群体自杀行为的具体风险因素，尤其是在美国和西欧以外的地区。本研究调查了波兰接受美沙酮维持治疗患者中自杀未遂的相关因素，并结合其他国家的研究结果对研究结果进行了解释。
方法
该研究基于从波兰一家美沙酮维持治疗诊所招募的240名个体样本。使用标准化测量方法对参与者进行访谈。
结果
与其他国家的研究一致，性虐待、抑郁、酒精依赖和冲动性与自杀未遂相关。此外，患有躯体合并症的患者自杀未遂的几率增加（比值比 = 2.6）。
结论
我们的研究结果表明，针对美沙酮维持治疗患者躯体问题的治疗方法可能具有益处。需要开展更多研究来识别、评估和理解阿片类药物依赖人群之间可能存在的文化和地区差异，以便更好地制定预防策略。
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