[Trypsin and alpha-amylase activity in the pancreas of guinea pigs. I. The influence of infective dose and duration of infection by Ascaris suum Goeze, 1782].

The studies were carried out on guinea pig males weighting about 280 g. The animals were infected with 5000 or 20,000 invasive eggs of Ascaris suum. On the 3-rd, 7-th, 10-th and 14-th day of invasion the animals were dissected. Lungs were weighted, and the number of Ascaris larvae was estimated using Baermann method. The activity of alpha-amylase (Fennel's method) and trypsin (Anson's method) were examined in pancreas homogenate. The infection of guinea pigs with A. suum larvae resulted in a decrease of amylase and trypsin activity in pancreas. The activities were the lowest at the 3-rd day of invasion for amylase and at the 7-th day for trypsin. The results obtained for the animals infected 5 or 20,000 invasive eggs A. suum did not differ statically.