[The prevalence of the HBsAg carrier state among pregnant women and its effect on newborn infants. IV. Our experience in using hepatitis B vaccine and hepatitis B immunoglobulin to immunize infants born to mothers who carry HBsAg].

59 children, born to mothers--carriers of HBsAg were immunized with hepatitis B vaccine (Gen HB-VAX) and hepatic B immunoglobulin (H-BIG) during 1988 in the municipality of Pleven. The results showed that GEN H-B-VAX possessed high immunological and epidemiological effect, manifested by the presence of anti-HBs in all examined children one month after conclusion of immunization. No diseases due to virus hepatitis B as well as persisting antigenemia were observed during the indicated 7-month period. Simultaneously there were one case with virus hepatitis B and 6 cases with persisting antigenemia in the control group of newborn infants.