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年轻女性的急性冠状动脉综合征——问题的规模及相关风险

Acute coronary syndromes in young women - the scale of the problem and the associated risks.

作者信息

Bęćkowski Maciej

机构信息

2 Clinic of Coronary Heart Disease - Cardinal Stefan Wyszyński Institute of Cardiology, Warsaw, Poland.

出版信息

Kardiochir Torakochirurgia Pol. 2015 Jun;12(2):134-8. doi: 10.5114/kitp.2015.52854. Epub 2015 Jun 30.

Abstract

Diseases of the cardiovascular system mainly affect elderly patients, but they are increasingly often encountered in young individuals. It is estimated that 1 in 20 patients with ischemic heart disease is under the age of 45 years. Only 20% of them are women. According to the PL-ACS register, cases of acute coronary syndromes in young women represent 0.6% of all acute coronary syndrome cases. The most common etiology is atherosclerosis (80%). Other causes include dissections and spasms of the coronary arteries as well as clotting disorders. Smoking tobacco is the most important risk factor, followed by hypertension, hyperlipidemia, and diabetes. The long-term prognosis is usually favorable, but it deteriorates significantly in the event of complications. The literature on this subject is not extensive. Most data come from non-randomized studies of young patients conducted regardless of sex. The purpose of this paper is to present the problem posed by acute coronary syndromes in young women.

摘要

心血管系统疾病主要影响老年患者,但在年轻人中也越来越常见。据估计,每20名缺血性心脏病患者中就有1人年龄在45岁以下。其中只有20%是女性。根据波兰急性冠状动脉综合征(PL-ACS)登记册,年轻女性急性冠状动脉综合征病例占所有急性冠状动脉综合征病例的0.6%。最常见的病因是动脉粥样硬化(80%)。其他原因包括冠状动脉夹层和痉挛以及凝血障碍。吸烟是最重要的危险因素,其次是高血压、高脂血症和糖尿病。长期预后通常良好,但如果出现并发症则会显著恶化。关于这一主题的文献并不广泛。大多数数据来自对年轻患者不分性别进行的非随机研究。本文的目的是阐述年轻女性急性冠状动脉综合征所带来的问题。

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