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血液透析系统私有化与患者生存率:来自东欧大型登记队列的报告

Hemodialysis system privatization and patient survival: a report from a large registry Eastern Europe cohort.

作者信息

Ştefan Gabriel, Podgoreanu Eugen, Mircescu Gabriel

机构信息

a Nephrology Department , "Carol Davila" University of Medicine and Pharmacy , Bucharest , Romania.

b Romanian Renal Registry , Bucharest , Romania and.

出版信息

Ren Fail. 2015;37(9):1481-5. doi: 10.3109/0886022X.2015.1077320. Epub 2015 Sep 3.

Abstract

BACKGROUND

There has been a rapid increase in incident and prevalent rates of hemodialysis (HD) patients in Romania following the 2004 system privatization, but little is known about the impact of privatization on patient outcomes.

METHODS

We retrospectively examined the outcome during 1 year of 8161 prevalent HD patients registered in the Romanian Renal Registry at 31 December 2011. Standardized mortality ratio (SMR) was calculated for each for-profit (FP) and non-profit (NP) HD provider.

RESULTS

The 12-month SMR across all HD chain providers was 1.27. FP Chain 1 and the "other" group had SMR similar to the reference level. The mortality rate was two times higher in public NP dialysis centers than the national reference. A stepwise Cox regression analysis identified older age, male gender, DN as primary renal disease and the HD chain provider to be independently associated with a higher mortality. Excepting patients treated by FP Chain 4, patients treated by all the other dialysis providers had a better outcome than those treated in NP facilities.

CONCLUSION

In conclusion, the increase in number of patients treated was not doubled by an increase in their survival. In the context of an expanding dialysis marketplace that tends to consolidate around large for-profit (FP) providers, further exploration of indicators associated with mortality may guide future healthcare policy to improve patient outcomes.

摘要

背景

2004年系统私有化后,罗马尼亚血液透析(HD)患者的发病率和患病率迅速上升,但关于私有化对患者结局的影响知之甚少。

方法

我们回顾性研究了2011年12月31日在罗马尼亚肾脏登记处登记的8161名HD患者1年期间的结局。计算了每家营利性(FP)和非营利性(NP)HD提供者的标准化死亡率(SMR)。

结果

所有HD连锁提供者的12个月SMR为1.27。FP连锁1和“其他”组的SMR与参考水平相似。公立NP透析中心的死亡率比国家参考值高出两倍。逐步Cox回归分析确定年龄较大、男性、糖尿病肾病作为原发性肾病以及HD连锁提供者与较高死亡率独立相关。除了由FP连锁4治疗的患者外,所有其他透析提供者治疗的患者比在NP设施中治疗的患者结局更好。

结论

总之,接受治疗的患者数量增加并没有使其生存率翻倍。在一个倾向于围绕大型营利性(FP)提供者整合的不断扩大的透析市场背景下,进一步探索与死亡率相关的指标可能会指导未来的医疗政策以改善患者结局。

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