高功能自闭症谱系障碍且智商>100 的成年人中海马体积增大：一项手动形态计量研究。
Increased hippocampal volumes in adults with high functioning autism spectrum disorder and an IQ>100: A manual morphometric study.
机构信息
Section for Experimental Neuropsychiatry, Clinic for Psychiatry and Psychotherapy, Medical Center, University of Freiburg, Hauptstr. 5, 79104 Freiburg, Germany; Freiburg Brain Imaging, Medical Center, University of Freiburg, Breisacher Str. 64, 79106 Freiburg, Germany.
Section for Experimental Neuropsychiatry, Clinic for Psychiatry and Psychotherapy, Medical Center, University of Freiburg, Hauptstr. 5, 79104 Freiburg, Germany; Freiburg Brain Imaging, Medical Center, University of Freiburg, Breisacher Str. 64, 79106 Freiburg, Germany; Universitäres Zentrum Autismus Spektrum, Clinic for Psychiatry and Psychotherapy, Medical Center, University of Freiburg, Hauptstr. 5, 79104 Freiburg, Germany.
出版信息
Psychiatry Res. 2015 Oct 30;234(1):152-5. doi: 10.1016/j.pscychresns.2015.08.002. Epub 2015 Aug 10.
Previous studies concerning the volumes of the amygdala and the hippocampus in autism spectrum disorders (ASD) show inconsistent results. We acquired magnetic resonance images of 30 individuals with ASD and individually matched controls. All participants had an IQ>100 to increase the likelihood of including non-syndromal forms of ASD. Manually defined amygdala volumes showed no significant group difference, while hippocampi were significantly enlarged in ASD. This finding is discussed with regard to the 'intense world hypothesis'.
先前有关自闭症谱系障碍（ASD）患者杏仁核和海马体体积的研究结果并不一致。我们获取了 30 名 ASD 患者和个体匹配对照者的磁共振图像。所有参与者的智商>100，以增加包括非综合征形式 ASD 的可能性。手动定义的杏仁核体积没有显示出显著的组间差异，而 ASD 患者的海马体明显增大。该发现结合“强烈世界假说”进行了讨论。
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