障碍物之间的离子电荷传输：新鲜切除的大块脑组织中的钠离子传导。
Ionic charge transport between blockages: Sodium cation conduction in freshly excised bulk brain tissue.
作者信息
Emin David, Akhtari Massoud, Ellingson B M, Mathern G W
机构信息
Department of Physics and Astronomy, University of New Mexico , Albuquerque, NM 87131, USA.
Semple Institutes for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California at Los Angeles , Los Angeles, CA 90095, USA.
出版信息
AIP Adv. 2015 Aug 11;5(8):087133. doi: 10.1063/1.4928652. eCollection 2015 Aug.
We analyze the transient-dc and frequency-dependent electrical conductivities between blocking electrodes. We extend this analysis to measurements of ions' transport in freshly excised bulk samples of human brain tissue whose complex cellular structure produces blockages. The associated ionic charge-carrier density and diffusivity are consistent with local values for sodium cations determined non-invasively in brain tissue by MRI (NMR) and diffusion-MRI (spin-echo NMR). The characteristic separation between blockages, about 450 microns, is very much shorter than that found for sodium-doped gel proxies for brain tissue, >1 cm.
我们分析了阻塞电极之间的瞬态直流和频率相关电导率。我们将此分析扩展到对新鲜切除的人脑组织大块样本中离子传输的测量，其复杂的细胞结构会产生阻塞。相关的离子电荷载流子密度和扩散率与通过MRI（NMR）和扩散MRI（自旋回波NMR）在脑组织中无创测定的钠阳离子局部值一致。阻塞之间的特征间距约为450微米，比在用于脑组织的钠掺杂凝胶替代物中发现的间距（>1厘米）短得多。
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