Department of Chemistry, Anna University, Chennai, Tamil Nadu 600025, India.
Department of Chemistry, Anna University, Chennai, Tamil Nadu 600025, India.
Carbohydr Polym. 2015 Nov 20;133:328-36. doi: 10.1016/j.carbpol.2015.07.015. Epub 2015 Jul 13.
The release kinetics of l-carvone loaded from electrospun poly(ϵ-caprolactone) (PCL) and Wheat cellulose (WC) blend were studied. WC was extracted from wheat straw, a cost effective agricultural waste by the acid hydrolysis method. A homogeneous solution of PCL-WC (13:3wt%) was optimized to produce beadless electrospun PCL-WC blend nanofibers. Further, WC and the prepared electrospun PCL-WC blend fibers were systematically characterized by ATR-FTIR, SEM, XRD, TGA, DTGA, and DSC measurements. The hydrophilic character of the blend fibers was analysed using swelling tests and contact angle measurements. The loading efficiency of l-carvone into the electrospun PCL-WC blend fibers was evaluated to be ∼70%. The in-vitro release of l-carvone from PCL-WC blend fibers followed Korsmeyer-Peppas kinetic model indicating the diffusion mechanism and the maximum release of l-carvone was found to be ∼84% over a period of 30h. These results would offer the prepared PCL-WC blend as an ideal fibrous mesh for fragrant antimicrobial textile applications.
研究了从静电纺聚（ε-己内酯）（PCL）和小麦纤维素（WC）共混物中负载 l-香芹酮的释放动力学。WC 通过酸水解法从麦秸中提取，这是一种具有成本效益的农业废弃物。优化了 PCL-WC（13:3wt%）的均相溶液，以生产无珠静电纺 PCL-WC 共混纳米纤维。此外，WC 和制备的静电纺 PCL-WC 共混纤维通过 ATR-FTIR、SEM、XRD、TGA、DTGA 和 DSC 测量进行了系统表征。使用溶胀试验和接触角测量分析了共混纤维的亲水性。评估了 l-香芹酮在静电纺 PCL-WC 共混纤维中的负载效率约为 70%。PCL-WC 共混纤维中 l-香芹酮的体外释放遵循 Korsmeyer-Peppas 动力学模型，表明释放机制为扩散机制，在 30h 的时间内，l-香芹酮的最大释放量约为 84%。这些结果将为制备的 PCL-WC 共混物提供理想的纤维网，用于芳香抗菌纺织品应用。
