[循环血液中的集落形成成纤维细胞前体]
[Colony-forming fibroblast precursors of the circulating blood].
作者信息
Luriia E A, Fridenshteĭn A Ia, Grosheva A G, Gleĭberman A
出版信息
Biull Eksp Biol Med. 1989 Dec;108(12):712-4.
PMID:2634446
Abstract
Colony-forming fibroblast precursors were detected in circulating blood of adult guinea pigs by CFUf in vitro colony assay. SFU amount to 0.9 +/- 0.2 (M +/- m) per 10(5) explanted leucocytes ranging from 0.04 X 10(-5) to 3.0 X 10(-5) for individual donors. The presence of collagen type I and lack of factor VIII antigen and of FC-receptors proved that CFU-derived colonies in the blood cultures were composed of fibroblasts.
摘要
通过体外集落形成单位（CFU）测定，在成年豚鼠的循环血液中检测到了集落形成性成纤维细胞前体。每10^5个接种的白细胞中，集落形成单位（SFU）的数量为0.9±0.2（平均值±标准差），个别供体的范围为0.04×10^(-5)至3.0×10^(-5)。I型胶原蛋白的存在以及VIII因子抗原和Fc受体的缺乏证明，血液培养物中由CFU衍生的集落是由成纤维细胞组成的。
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