Rapkiewicz Amy, Hood Brian, Hutchins Kenneth
New York University Langone Medical Center, New York, NY, 10016.
Uniformed Services University of Health Sciences, San Antonio, TX, 78234.
J Forensic Sci. 2016 Jan;61 Suppl 1:S268-70. doi: 10.1111/1556-4029.12934. Epub 2015 Sep 8.
Hydrophilic polymers are used to coat catheters and other intravascular devices. In general, these polymers have many salutary properties; however, in some instances, fragmentation of hydrophilic polymers coating intravascular devices can occur with fatal consequences. This report details the histopathologic changes in the lung seen following polymer fragmentation and embolization from a central venous catheter. Polymer emboli detected microscopically are intravascular and consist of basophilic, lamellated, and nonrefractile elements. Typically, an inflammatory response is present to a variable degree. Embolization can result in severe tissue injury with ischemia and infarction.
亲水性聚合物被用于包裹导管及其他血管内装置。一般来说，这些聚合物具有许多有益特性；然而，在某些情况下，血管内装置上的亲水性聚合物涂层可能会发生破碎，从而导致致命后果。本报告详细描述了中心静脉导管聚合物破碎和栓塞后肺部的组织病理学变化。显微镜下检测到的聚合物栓子位于血管内，由嗜碱性、层状且无折光性的成分组成。通常会出现不同程度的炎症反应。栓塞可导致严重的组织损伤，伴有缺血和梗死。
