Rodríguez J, Horzella R, Zolezzi P
Rev Chil Pediatr. 1989 Jan-Feb;60(1):36-9.
The case of a 13 year old girl is presented, who developed intense pain in extremities and experienced marked weight loss after an acute upper respiratory tract infection. Roentgenograms revealed a diffuse periosteal reaction, most intensely affecting long bones. Principal laboratory findings were a slight normocytic, normochromic anemia; high erythrocyte sedimentation rate; medullar plasmocytosis and dysproteinemia, with a large increase in plasma gammaglobulin concentration. Clinical recovery and normalization of roentgenograms and laboratory parameters were observed eleven months after the acute episode, with no intervening therapeutic measures. This case matches Goldbloom's syndrome, described originally in two children in 1966. Only 3 other cases have been reported in the literature.
本文报告了一名13岁女孩的病例，该女孩在急性上呼吸道感染后出现四肢剧痛，并伴有明显体重减轻。X线片显示弥漫性骨膜反应，以长骨受累最为明显。主要实验室检查结果为轻度正细胞正色素性贫血、红细胞沉降率升高、骨髓浆细胞增多和蛋白异常血症，血浆γ球蛋白浓度大幅升高。急性发作11个月后，观察到临床康复以及X线片和实验室指标恢复正常，期间未采取任何治疗措施。该病例符合1966年最初在两名儿童中描述的戈德布卢姆综合征。文献中仅另有3例报告。
