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毛霉菌病所致纵隔炎和支气管穿孔

Mediastinitis and Bronchial Perforations Due to Mucormycosis.

作者信息

Dhooria Sahajal, Agarwal Ritesh, Chakrabarti Arunaloke

机构信息

Departments of *Pulmonary Medicine †Medical Microbiology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

出版信息

J Bronchology Interv Pulmonol. 2015 Oct;22(4):338-42. doi: 10.1097/LBR.0000000000000170.

DOI:10.1097/LBR.0000000000000170
PMID:26348693
Abstract

Diabetes mellitus is the most common predisposing condition for mucormycosis, which is emerging as an important invasive fungal infection worldwide. Isolated mediastinitis is a very rare presentation of mucormycosis. A 57-year-old woman with uncontrolled type 2 diabetes mellitus and ketoacidosis presented with septic shock and was subsequently found to have mucor mediastinitis with multiple bronchial perforations. The organism was identified as Rhizopus oryzae with the help of DNA sequencing.

摘要

糖尿病是毛霉菌病最常见的诱发因素,毛霉菌病在全球正成为一种重要的侵袭性真菌感染。孤立性纵隔炎是毛霉菌病非常罕见的一种表现形式。一名57岁的2型糖尿病控制不佳且伴有酮症酸中毒的女性患者,出现感染性休克,随后被发现患有伴有多处支气管穿孔的毛霉纵隔炎。借助DNA测序将该病原体鉴定为米根霉。

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引用本文的文献

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Coinfection of pulmonary tuberculosis and mucormycosis in a patient with poor controlled diabetes mellitus: A case report.一名糖尿病控制不佳患者的肺结核与毛霉病合并感染:病例报告
Radiol Case Rep. 2023 Sep 18;18(11):4202-4205. doi: 10.1016/j.radcr.2023.08.091. eCollection 2023 Nov.
2
GRP78 and Integrins Play Different Roles in Host Cell Invasion during Mucormycosis.GRP78 和整合素在毛霉病宿主细胞侵袭中发挥不同作用。
mBio. 2020 Jun 2;11(3):e01087-20. doi: 10.1128/mBio.01087-20.
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Idiopathic Mediastinal Fibrosis: a Systemic Immune-Mediated Disorder. A Case Series and a Review of the Literature.
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