Gounis Matthew J, van der Marel Kajo, Marosfoi Miklos, Mazzanti Mary L, Clarençon Frédéric, Chueh Ju-Yu, Puri Ajit S, Bogdanov Alexei A
From the New England Center for Stroke Research (M.J.G., K.v.d.M., M.M., F.C., J.-Y.C., A.S.P.) and Laboratory of Molecular Imaging Probes (M.L.M., A.A.B.), Department of Radiology, University of Massachusetts Medical School, Worcester.
Stroke. 2015 Oct;46(10):2991-7. doi: 10.1161/STROKEAHA.115.008229. Epub 2015 Sep 8.
Imaging inflammation in large intracranial artery pathology may play an important role in the diagnosis of and risk stratification for a variety of cerebrovascular diseases. Looking beyond the lumen has already generated widespread excitement in the stroke community, and the potential to unveil molecular processes in the vessel wall is a natural evolution to develop a more comprehensive understanding of the pathogenesis of diseases, such as ICAD and brain aneurysms.
对大型颅内动脉病变中的炎症进行成像,可能在多种脑血管疾病的诊断和风险分层中发挥重要作用。超越管腔层面的研究已经在中风领域引起了广泛关注,揭示血管壁分子过程的潜力是自然的发展趋势,有助于更全面地理解诸如颅内动脉粥样硬化性疾病(ICAD)和脑动脉瘤等疾病的发病机制。