Wiór H, Tesarz Z
Probl Med Wieku Rozwoj. 1979;8:144-51.
An analysis of frequency of congenital malformation observed among the neonates in 1972 in Poland has been performed on the basis of individual statistical cards filled in by medical personnel for each hospital delivery. Among 486.404 live- and stillborns, 7647 neonates with congenital malformations have been noted, which corresponds to the index of 15,72 per 1000 total births. The most frequently observed malformations were: congenital anomalies of limbs (755)-4,63/1000 total births, mostly congenital dislocation of hip; congenital malformations of the nervous system--2,11 degrees/00; of heart and circulatory system--1,89 degrees/00. Relatively low index of anencephaly has been noted--0,61/1000 total births. Among newborns of mothers from rural areas anencephaly and congenital hydrocephalus were more frequently noted. In urban areas congenital anomalies of limbs and congenital anomalies of skin, hair and nails were diagnosed more frequently. Frequency of congenital malformations among neonates of very young (less than 20 or less than or equal to 19 y.) and older (greater than equal to 35 y.) mothers was higher than in the intermediate age groups. Influence of mother's age on the frequency of particular malformations was analysed. Among neonates with congenital malformations born alive percentage of sexes was similar to the general population of live borns, whereas among stillbirths and prematures unable to live with congenital malformations--females were more frequent.
基于医务人员为每家医院分娩填写的个人统计卡片,对1972年波兰新生儿中观察到的先天性畸形频率进行了分析。在486404例活产儿和死产儿中,发现7647例患有先天性畸形的新生儿,这相当于每1000例总出生数中有15.72例。最常观察到的畸形有:肢体先天性异常(755例)——每1000例总出生数中有4.63例,主要是先天性髋关节脱位;神经系统先天性畸形——2.11‰;心脏和循环系统先天性畸形——1.89‰。无脑儿的发生率相对较低——每1000例总出生数中有0.61例。在农村地区母亲所生的新生儿中,无脑儿和先天性脑积水更为常见。在城市地区,肢体先天性异常以及皮肤、毛发和指甲先天性异常的诊断更为频繁。非常年轻(小于20岁或小于等于19岁)和年龄较大(大于等于35岁)母亲所生新生儿的先天性畸形发生率高于中年年龄组。分析了母亲年龄对特定畸形发生率的影响。在患有先天性畸形的活产新生儿中,男女比例与活产儿的总体比例相似,而在患有先天性畸形的死产儿和无法存活的早产儿中,女性更为常见。