Kaiser S, Kramer M, Thiel C
Dr. Susanne Kaiser, Klinikum Veterinärmedizin, Klinik für Kleintiere (Chirurgie), der Justus-Liebig-Universität Gießen, Frankfurter Straße 108, 35392 Gießen, E-Mail:
Tierarztl Prax Ausg K Kleintiere Heimtiere. 2015;43(5):291-8. doi: 10.15654/TPK-150029. Epub 2015 Sep 10.
Case series of four dogs in which extensive bite wounds had been treated using octenidine dihydrochloride (Octenivet® or Octenisept®) flushing. The dogs subsequently developed severe local complications.
Retrospective evaluation of clinical symptoms, diagnostics, therapy and course of the disease.
In four dogs, severe necrosis and persistent edematous changes of the treated area developed after the application of octenidine dihydrochloride. The clinical course was comparable to complications described previously in human medicine. Therapy was protracted and complicated by secondary wound infection.
Irrigation of deep wounds, particularly bite wounds, using octenidine dihydrochloride without drainage may lead to persistent edematous changes, inflammatory reactions and necrosis. The inappropriate application of octenidine dihydrochloride for wound irrigation should be avoided in veterinary medicine.
对四只犬的病例系列进行研究，这些犬的广泛咬伤伤口使用二盐酸奥替尼啶（Octenivet®或Octenisept®）冲洗治疗。这些犬随后出现了严重的局部并发症。
对临床症状、诊断、治疗及疾病过程进行回顾性评估。
在四只犬中，应用二盐酸奥替尼啶后，治疗区域出现严重坏死和持续性水肿变化。临床过程与之前人类医学中描述的并发症相似。治疗过程漫长且因伤口继发感染而复杂化。
使用二盐酸奥替尼啶冲洗深部伤口，尤其是咬伤伤口且不进行引流，可能会导致持续性水肿变化、炎症反应和坏死。在兽医学中应避免不恰当地使用二盐酸奥替尼啶进行伤口冲洗。
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